in recent years, the relationship between insertion and deletion (indel) polymorphisms in promoter region (23 bp) and intron 1 (12 bp) of prnp gene (prion protein coding gene) and their relationship to susceptibility of classical bovine spongiform encephalopathy (bse) have been reported. insertions of these two polymorphisms increase resistance to classical bse, while the deletions of these two...

INTRODUCTION Breast cancer is a public health problem that is increasing throughout the world especially in developing countries. The study was aimed at assessing the knowledge of breast cancer and practice of breast self examination (BSE) among female senior secondary school students in the municipal council area of Abuja, Nigeria. METHODS This descriptive cross sectional study was carried o...

This cross-sectional and descriptive study was aimed to evaluate women breast self-examination (BSE) practice and effects of a planned educational programme for breast cancer and BSE. The samples of the study consisted 266 women. The study data were collected by a questionnaire in six months periods as two times in a month in which the periods were defined and announced to all women. After that...

The H-type of atypical bovine spongiform encephalopathy (H-BSE) was serially passaged in bovinized transgenic (TgBoPrP) mice. At the fourth passage, most challenged mice showed a typical H-BSE phenotype with incubation periods of 223 ± 7.8 days. However, a different phenotype of BSE prion with shorter incubation periods of 109 ± 4 days emerged in a minor subset of the inoculated mice. The latte...

BACKGROUND Despite the causal association between variant Creutzfeldt - Jakob disease and bovine spongiform encephalopathy (BSE), bovine origin graft materials are widely used during dental surgical procedures. The aim of this study was to assess the risk of BSE transmission through anorganic bovine bone substitutes. METHODS Electronic database of MEDLINE was searched to identify relevant stu...

Bovine spongiform encephalopathy (BSE) prions were responsible for an unforeseen epizootic in cattle which had a vast social, economic, and public health impact. This was primarily because BSE prions were found to be transmissible to humans. Other species were also susceptible to BSE either by natural infection (e.g., felids, caprids) or in experimental settings (e.g., sheep, mice). However, ce...

The in vitro amplification of prions by serial protein misfolding cyclic amplification has been shown to detect PrPSc to levels at least as sensitive as rodent bioassay but in a fraction of the time. Bovine spongiform encephalopathy is a zoonotic prion disease in cattle and has been shown to occur in 3 distinct forms, classical BSE (C-BSE) and 2 atypical BSE forms (L-BSE and H-BSE). Atypical fo...

On May 1, 2003, the American Cancer Society (ACS) published new guidelines for breast cancer screening (ACS, 2003). Although mammography guidelines were retained, the recommendations for breast selfexamination (BSE) were revised significantly. The 1997 guidelines stated that, starting at age 20, women should perform BSE monthly. New guidelines state that, beginning in their 20s, women should be...

This paper discusses the development of a set of specifications for a development methodology for educational multimedia, specifically for the development of a prototype educational multimedia application for Breast Self Examination (BSE) training. In the paper, the need for BSE training is examined and BSE is briefly presented. Our focus, however, is to show how the development of a multimedia...

While breast self-examination (BSE) frequency has received extensive research attention, proficiency has been less frequently addressed. Moreover, BSE proficiency among women at increased risk has not been adequately examined. Assessment of BSE proficiency is critical in determining the value of BSE with mammography and clinical breast examination in the early detection of breast cancer. BSE pr...