Bronchiectasis unrelated to cystic fibrosis (non-CF bronchiectasis) has become a major respiratory disease in developing nations. The dilated mucus filled airways promote bacterial overgrowth followed by chronic infection, bronchial inflammation, lung injury and re-infection Accurate pathogen identification antimicrobial susceptibility allowing appropriate treatment, turn, may break this viciou...

Abstract Background Bronchiectasis is a chronic pulmonary disease characterized by widened, malformed bronchi, with profuse expectoration and impaired quality of life. COPD ILD are common co-morbidities bronchiectasis. Methods The present study evaluated the clinical, laboratory& radiological characteristics with/without A hospital-based, retrospective was conducted for 1 year. Results tota...

In an effortto determine potential diagnostic usefulness of bronchiectasis adjacent to pulmonary coin lesions, 39 cases were evaluated by chest roentgenogram and bronchography. Ten of 17 benign lesions demonstrated localized adjacent bronchiectasis. Twenty-one of 22 malignant coin lesions failed to demonstrate that finding. Localized bronchiectasis adjacent to a “coin lesion” is a useful indica...

BACKGROUND Bronchiectasis is characterised by a widening of the airways, leading to excess mucus production and recurrent infection. It is more prevalent in women and those in middle age. Many patients with bronchiectasis do not adhere to treatments (medications, exercise and airway clearance) prescribed for their condition. The best methods to change these adherence behaviours have not been id...

PURPOSE Bronchiectasis in children is still one of the most common causes of childhood mortality in developing countries. The aim of this study was to investigate the epidemiological characteristics, clinical features, underlying etiologic factors, and distinct change in the management of patients with bronchiectasis at Asan Medical Center Children's Hospital of Seoul. METHODS A retrospective...

Bronchiectasis is defined by permanent and abnormal widening of the bronchi. This process occurs in the context of chronic airway infection and inflammation. It is usually diagnosed using computed tomography scanning to visualize the larger bronchi. Bronchiectasis is also characterized by mild to moderate airflow obstruction. This review will describe the pathophysiology of noncystic fibrosis b...

BACKGROUND Bronchiectasis continues to be one of the major causes of morbidity and mortality in developing countries, with a probably underestimated higher prevalence than in developed countries. OBJECTIVE To assess the clinical profile of adult patients with bronchiectasis. METHODS We retrospectively reviewed the clinical, radiologic, and physiologic findings of 304 patients with bronchiec...

The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations. We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate previous findings of bacterial colonization and inflammation to the degree of ...

BACKGROUND Mosaicism and hyperinflation are common pathophysiologic features of bronchiectasis. The magnitude of ventilation heterogeneity might have been affected by the degree of hyperinflation. Some studies have evaluated the discriminative performance of lung clearance index (LCI) in bronchiectasis patients, but the additive diagnostic value of hyperinflation metrics to LCI is unknown. OB...

B eyond any reasonable doubt, one of the greatest achievements of medicine in the last century has been the successful reduction of morbidity and mortality due to infectious disease. In 1938, a landmark paper in the Edinburgh Medical Journal by COOKSON and MASON [1] highlighted the high lethality of bronchiectasis even before the fourth decade of life [1, 2]. Thanks to improved hygiene measures...