We present the case of an 80-year-old man who was admitted for anemia, back pain and progressive weakness. After a workup of clinical and laboratory data, the final diagnosis was multiple myeloma. The bone marrow aspirate revealed 53% myeloma cells with peculiar and rare morphological features: numerous large asurophilic--bright red granules--mucopolizaccharides and immunoglobulins secreted and...

We report the case of a 66-year-old man with Takayasu arteritis who developed photic and postprandial amaurosis occurring at a corticosteroid dose <40 mg per day, despite concurrent methotrexate. The amaurosis resolved with correction of anemia by packed red blood cell transfusion. Marginal retinal perfusion in Takayasu arteritis may precipitate symptomatic hypoxia as a result of eating a meal ...

The broaden-and-build theory of positive emotions predicts that positive emotions broaden the scopes of attention and cognition, and, by consequence, initiate upward spirals toward increasing emotional well-being. The present study assessed this prediction by testing whether positive affect and broad-minded coping reciprocally and prospectively predict one another. One hundred thirty-eight coll...

was more esteemed during life, or more regretted on his death in 1833 (from influenza, then so prevalent), than this truly good man, the leading features of whose character are well pourtrayed in a sketch of his career drawn up by his distinguished son-in-law, Dr. Richard Bright, in-^e twelfth volume of the Medical Gazette. The rare honour ofS*k. statue?one of the best works of the late Mr. Beh...

Human circadian rhythms were once thought to be insensitive to light, with synchronization to the 24-hour day accomplished either through social contacts or the sleep-wake schedule. Yet the demonstration of an intensity-dependent neuroendocrine response to bright light has led to renewed consideration of light as a possible synchronizer of the human circadian pacemaker. In a laboratory study, t...

This paper proposes a new approach to building falsename-proof (FNP) combinatorial auctions from those that are FNP only with single-minded bidders, each of whom requires only one particular bundle. Under this approach, a general bidder is decomposed into a set of single-minded bidders, and after the decomposition the price and the allocation are determined by the FNP auctions for single-minded...

We present an interim report on Chandra HRC-S calibration observations of Vega, an Xray–dark and UV-bright star. The purpose of the observations is to monitor the UV response of the detector, and recently it has acquired further importance as a means to track the effects of increased radiation dosage on the UV/ion-shield of the detector. We find no conclusive evidence that leaving the HRC door ...

A 78-year-old man was admitted to hospital due to massive, bright red hematemesis. As he was hemodynamically unstable, vigorous resuscitation procedures were initiated. Esophagogastroduodenoscopy (EGD) showed a large Mallory– Weiss lesion and a necrotic polypoid lesion about 4 cm below the upper esophageal sphincter (Figure 1). No active bleeding was visible. Six hours later, there was again an...