Introduction: The proton beam produced in particle accelerators has an appropriate therapeutic potential. In this research, proton therapy of breast cancer is simulated using the MCNPX code in a MIRD phantom, also the contribution of scattered neutron dose during the proton therapy were calculated for the Heart, Lung and Liver.   Materials and Methods: For si...

BACKGROUND The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this study was to compare coverage of computed tomography (CT)-based breast and boost planning target volumes (PTV), absolute volumes irradiated, and dose delivered to the organs at ri...

Introduction: Delivering maximum dose to tumor and minimum dose to normal tissues is the most important goal in radiotherapy. According to ICRU, the maximum acceptable uncertainty in the delivered dose compared to the prescribed dose should be lower than 5%, and this is because of the relationship between absorbed dose, tumor control and normal tissue damage. Absorbed dose accuracy is investiga...

Background: Intensity Modulated Radiotherapy (IMRT) can improve radiotherapy (RT) results by improving healthy tissue sparing. Additionally, IMRT provides more consistent dose deliveries and suppresses secondary tumor formation. RT is a principal treatment in breast cancer (BC). Aim: To evaluate the outcome of the Radiotherapy Plans (RTP) that use IMRT technique to left breast and other organs,...

Breast cancer is the most common neoplasm and leading cause of death in women worldwide. Although 5-fluorouracil a conventional chemotherapeutic agent for breast treatment, its use may result severe side effects. Thus, there widespread interest lowering drawbacks, without affecting therapeutic efficacy by concomitant with natural products. Herein, we aimed at evaluating whether α-mangostin, ant...

The purpose of this study was to demonstrate asymmetric radiation dose distribution to the breasts in coronary angiography. Gafchromic XR-QA2 film was used as an area dosimeter to capture the asymmetric dose distribution to the breasts at various tissue depths in an anthropomorphic phantom. A selection of tube angulations were used under a controlled experiment and during a mock coronary angiog...

Introduction: Recently, the use of nanoparticles has increased for many purpose in medicine. One of these is using the nano particles in shields structure to protect sensitive organs such as breast which placed inside the field of chest CT scan and receives high dose. The aim of this study was the use of nano Bi2O3 to making shield for protection breast in chest CT examination ...

Purpose: To examine the ability of computer planning systems to calculate the dose to the breast correctly in three dimensions. Both the absolute dose at the center of the breast and the accuracy of the isodose distributions were investigated. Methods and Materials: Measurements were performed in a water-filled breast phantom using an ionization chamber. Thirty-six sets of data obtained during ...

This study aims to determine the average absorbed dose of radiation in glandular tissue during mammography and to investigate factors that influence the average glandular dose, particularly the local distribution of glandular tissue within the breast and breast skin thickness. An EGSnrc Monte Carlo code and associated codes were employed in the simulation. The breast voxel models used consist o...