introduction: radiation therapy following breast conserving surgery is one of the most common procedures performed in any radiation oncology department. a tangential parallel-opposed pair is almost always the technique of choice for this purpose. this technique is often performed based on 3d treatment planning. the aim of this study was to compare 3d treatment planning for two different energie...

Objective: To determine the impact of tumor biology on rates of breastconserving surgery and pathologic complete response (pCR) after neoadjuvant chemotherapy. Background: The impact of tumor biology on the rate of breast-conserving surgery after neoadjuvant chemotherapy has not been well studied. Methods: We used data from ACOSOG Z1071, a prospective, multicenter study assessing sentinel lymph...

Optimal oncological results and patient outcomes are achieved in surgery for early breast cancer with conserving (BCS) where this is appropriate. A limitation of BCS when cancer...

background: seroma formation is a common complication after breast cancer surgery. several techniques such as tube drainage, fibrin sealant and suturing methods have been employed to prevent or reduce seroma formation. capitonnage, a suturing method widely used following hydatid cyst removal, has been used after breast surgery in limited studies. our aim was to compare the effectiveness of tube...

PURPOSE Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS A total of 178 patients who received breast-conserving surgery and postoperat...

Breast cancer is a disease primarily of older women. The cumulative risk for this disease reaches its maximum well into the ninth decade of life (7). It is also a serious disease in older women. The approximate 10-year risk of disease recurrence for women 70 years of age or older who are lymph node negative with 1to 5-cm tumors is 20%-30%; the risk for women with one to three positive lymph nod...

SUMMARY Corrective surgery following breast-conserving surgery is generally challenging due to severe fibrosis induced by postoperative radiotherapy. Although use of the latissimus dorsi myocutaneous flap offers a safe and reliable option, exposure of the skin paddle to the skin surface is often inevitable to achieve correction of nipple-areola complex malposition, leaving conspicuous, patchwor...

Most breast cancer recurrences occur in the surgical scars or within other quadrants of the same breast. Isolated tumour recurrence occurring in the nipple after breast-conserving surgery and radiotherapy is extremely unusual. The reason for this is unknown, but is speculated to be due to involved surgical margins or an occult involvement of the nipple-areolar complex in a breast cancer of the ...

In women diagnosed with breast cancer and testing positive for a BRCA1/2 mutation, decisions as to whether to undergo prophylactic risk-reduction surgery may differ from those women who test positive in a presymptomatic phase. Eighty-four women were identified who had undergone genetic testing at the time of breast cancer diagnosis. The study group consisted of 46 of these women who had initial...