objective: breast cancer is the most common cancer among women in the world. early diagnosis of this cancer is a key element for its treatment. one of the approaches for diagnosis of breast cancer is detection of its tumour-associated markers. hence, her2 has been the main focus of the researches in the field. materials and methods: for diagnosis of her2 overexpression, monoclonal antibodies (m...

Background: Breast cancer is an important cause of cancer death among women all over the world. Even in places with low incidence there are reports of an increase in the number of breast cancer patients. The aim of the present study was to report the demographic aspects of breast cancer among patients referred by surgeons for adjuvant therapy in a private cancer clinic during the past five year...

 Background: Breast cancer is one of the most common cancer of women in the world.  Although different genetic alteration has been reported in this malignancy, but P 53 gene  mutations has more frequency. P 53 gene is one of the most important suppressor genes and it  play a central role in breast cancer and detecting of mutations in this gene would be very helpful in understanding of genetic m...

results strong participation was associated with a younger age, higher educational level, higher incomes, previous history of cancer, previous family history of cancer, one or two prior mammographies, more correct recognitions of mammography, recall rate, and breast cancer risk. if the false-positive result occurred, 83.9%, 81.9% and 77.3% of the women agreed or strongly agreed to participate i...

Background & objective: Breast cancer is the leading cause of cancer related death in females. Sphingosine kinase 1 (SPHK1) and its product sphingosine-1-phosphate (S1P) are the essential key regulator molecules in breast cancer through their ability to promote cell proliferation, angiogenesis, cell proliferation, and lymphagiogenesis. SPHK1 i...

patients and methods in this cross-sectional study, data of 584 female patients (mean age of 45.9 years) referred to breast cancer research center (tehran, iran) were analyzed anonymously. spss and norm softwares (2.03) were used for data transformation, running and interpretation of cca and replacing missing values, respectively. data were obtained from breast cancer research center, tehran, i...

background breast cancer is the most common cancer among women worldwide. based on the latest iranian national cancer department report, the total number of women registered with breast cancer was 6976 cases during 2007. five year survival is one of the indicators used for evaluation of the quality for care to different types of malignancies including breast cancer. objectives the aim of this s...

abstract background: breast cancer as a most common organ cancer in women is the first cause of death among women with 40-45 years old. the only way to control this disease is early detection that it can be treated in about 90% of women with breast cancer. the best way for early detection of breast cancer is screening, and the best accessible way is breast self examination (bse). considering th...