Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign and locally invasive tumor. Massive bleeding because of vascularity of tumor and postoperative recurrence are potential problems of management. Endonasal approach reduces the rate of postoperative recurrence, intraoperative bleeding, and complications of surgery, time of operation and duration of hospitalization. In this article, we r...

Malignant gliomas are highly invasive brain tumors with the occurrence of multiple microglia/macrophages in the tumor microenvironment. Macrophages/microglia that found in glioma microenvironment, as tumor-infiltrating immune cells, can play a harmful role in tumor progression. In addition, glioblastoma multiforme (GBM) contains multiple aberrant differentiation and tumorigenic cancer stem cell...

Glioblastoma multiforme (GBM), the most common malignant primary brain tumor in adults, carries a poor prognosis, with median survival generally less than 1 year. Although initial therapy often eradicates the bulk of the tumor, disease recurrence, usually within 2 cm of the original tumor, is almost inevitable. This may be due to a failure of current therapies to eradicate viable chemotherapy- ...

The aim of the study was to assess the rate, pattern, and time of recurrence in patients with triple-negative breast cancer (TNBC) and to evaluate factors influencing recurrence and overall survival in this group of patients. Out of 2,534 consecutive breast cancer patients diagnosed between January 2005 and December 2006, 228 (9 %) were TNBC (ER/PR/HER2-negative). The clinicopathological charac...

OBJECTIVE To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy. METHODS Fifty-five patients with suspected brain tumor recurrence or necrosis after radiotherapy underwent MRI, F-18 FDG, and 11C-choline PET/CT examinations, and all the patients were followed up for at least 11 mont...

background : the association of the mobile phone use and risk of brain tumor remains controversial among radiationepidemiologists. methods : we hypothesized if an association between brain tumor and mobile phone use exists, this association will be manifested as a cohort effect (as a proxy of association between mobile phone use and brain tumor) in the incidence rates of brain tumor during the ...

Abstract Resistance to genotoxic therapies and tumor recurrence are hallmarks of glioblastoma (GBM), an aggressive brain tumor. Here, we explore the functional drivers post-treatment recurrent GBM. By conducting genome-wide CRISPR-Cas9 screens in patient-derived GBM models, uncover distinct genetic dependencies cells that were absent their patient-matched primary predecessors, accompanied by in...

UNLABELLED We investigated the impact of (18)F-DOPA brain PET/CT on the clinical management of patients with known or suspected brain tumors. METHODS A prospective survey of referring physicians was conducted. A pre-PET questionnaire inquired about indication, tumor histology or grade, level of suspicion for tumor recurrence, and planned management. Early post-PET questionnaires asked referri...

Cardiac myxoma is the most common benign tumor of the heart. Complete surgical removal of the myxoma is usually curative. However, low incidence of recurrence and metastasis has been reported with the brain being the most common site of cardiac myxoma metastasis (1). We report a rare case of delayed multiple cerebral metastases from the completely resected cardiac myxoma without evidence of loc...