introduction brain trauma is one of the most common causes of hospitalization, disability, and mortality of people aged 15 to 74 years in nowadays societies. on the other hand, nowadays, different categories of stem cells are used to treat different kinds of diseases. bm-mscs, are center of scientific research because of their high differentiation and proliferation ability. methods:  stem cells...

Adult neurogenesis is a process of producing nerve cells from their progenitor that occurs in some areas in the brain such as the hypothalamus. Low activity in this area plays a role in neural degeneration and diseases such as multiple sclerosis, epilepsy and depression. MS is a neurodegenerative disease with a permanent disability that the main reason for it is axonal degeneration and neuronal...

objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...

Metabolic changes in the brain stem were measured at the time when oxygen deprivation-induced respiratory depression occurred. Eucapnic ventilation with 8% oxygen in vagotomized urethan-anesthetized rats resulted in cessation of respiratory drive, monitored by recording diaphragm electromyographic activity, on average within 11 min (range 5-27 min), presumably via central depressant mechanisms....

Acute experiments on cats under chloralose anesthesia were designed to study the role of the brain stem in the transmission of the interhemispheric delayed response (IDR). Experiments on interaction of potentials recorded in brain stem and at cortex led to the conclusion that the IDR is relayed to the contra-lateral hemisphere via routes which pass through the general area of the mesencephalic ...

background: brainstem hemorrhage was first described by cheyne in 1812 in a pathological study of patients presenting with lethargy and coma. in 1877 bode reviewed the findings of 67 patients reported in the literature (1). in the united states, the incidence of closed head injury is estimated to be approximately 200 cases per 100,000 persons per year. the financial burden of head injuries in t...

Objective: Anastasis, a process that has been discovered recently, halts apoptosis, and thus, recovers the survival functions of cells. It may be suggested anastasis is related to cancer progression, especially in stem cells which are responsible for therapy resistance, metastasis, recurrence. In this study, investigation phenomena its effect on stemness gene expressions brain cancer-related ai...