there are only a few, non-evidence based, neuroprotective strategies for treatment and prevention of brain injuries after closed head trauma. to establish new therapy strategies, a novel animal model is needed. the aim of our investigation was to link standardized small animal models and actual patient medical care. data of experimental small animal studies often cannot be transferred to cns in...

background access to appropriate images of fetal brain can greatly assist to diagnose of probable abnormalities. the aim of this study was to compare the suitability of t2-true fast imaging with steady state free precession (t2-trufi), and t2-half-fourier acquisition single-shot turbo spin-echo (t2- haste( magnetic resonance imaging (mri) to extract the fetal brain using the level set algorithm...

how to cite this article: karimzadeh p, ahmadabadi f, jafari n, shariatmadari f, nemati h, ahadi a, karimi dardashti s, mirzarahimi m, dastborhan z, zare noghabi j. study on mri changes in phenylketonuria in patients referred to mofid hospital. iran j child neurol. 2014 spring 8(2):53-56. objective phenylketonuria is one of the most common metabolic disorders and the first known cause of mental...

Background: Patients with leukemia are facing more complications in order to achieve longer survival. We aimed to evaluate the frequency of central nervous system abnormalities (CNS) on MRI of children with acute lymphoblastic leukemia (ALL). Methods: Sixty-six children with diagnosis of ALL aged 2-18 years were recruited. Non-contrast sequences of brain MRI in addition to diffusion weighted i...

purpose: to determine the clinical and paraclinical features of multiple sclerosis (ms) in patients presenting for the first time with optic neuritis. methods:  in this descriptive study, 35 patients with clinical evidence of optic neuritis were enrolled. our evaluation included a neurological examination, visual evoked potentials (vep), brainstem-auditory evoked potentials (baep), and brain mr...

introduction an unusual incidence of tuberculosis in different parts of the body is called tuberculomas. the rate of brain tuberculosis is rare. case presentation the following case of tuberculamas of the brain, presented by enhancing rings of meninges, is reported because of its rarity. it was a case of brain tuberculomas in a 15-year-old girl with primary symptoms of headache and general weak...

we report an unusual case of hemimegalencephaly (hmg) associated with ipsilateral congenital-infiltrating lipomatosis of the face in a five-month-old boy. hemimegalencephaly is a rare but unique malformation characterized by enlargement of all or parts of a cerebral hemisphere. the affected hemisphere may have focal or diffuse neuronal migration defects, with areas of polymicrogyria, pachygyria...

background: with regard to the high prevalence of schizophrenia, research on brain structural changes in this disease has been one of the interesting issues among the medical scientists. in this research, brain mri findings of schizophrenic patients have been compared with non-schizophrenic ones. methods: this study was an analytic-comparative one in which two groups of schizophrenic and non-sc...

typical nmo is characterized by simultaneous or sequential acute transverse myelitis and optic neuritis. spinal cord lesions extending over 3 or more vertebral segments and normal brain imaging are the typical mri findings in nmo. in typical cases with positive nmo antibody the diagnosis is easy but in seronegative and atypical cases with different clinical manifestations and mri features the d...