traumatic brain injury (tbi) is physical damage to the brain structure which has a high global rate of mortality and morbidity. tbi can cause intense inflammatory response due to accumulation of leukocytes in cerebral matrix and activation of microglia. microglia can differentiate into m1 macrophages or m2 macrophages following the changes in biochemical properties of brain tissue. m1 sub type ...

Background: The present study assesses independent predictors of clinically important traumatic brain injury (ciTBI) in order to design a prognostic rule for identification of high risk children with mild head injury. Materials and Methods: In a retrospective cross-sectional study, 3,199 children with mild traumatic brain injury (TBI) brought to emergency ward of three hospitals in Tehran, Iran...

objective: this study was designed to examine the effects of human umbilical cord matrix stemcell (hucmsc) administration in rats for 6 week after traumatic brain injury (tbi). materials and methods: adult male wistar rats (n = 30) were injured with controlled cortical impact device and divided into three groups. the treatment groups (n = 10 each) were injected with 2 × 106 (2 milion) intraveno...

objectives the aim of this study was to present the incidence and characteristics of repeated tbi (rtbi) in iranian patients. patients and methods during one year, all admitted tbi patients with prior tbi history were enrolled into the study. in each patient, data such as age, gender, past medical history, injury cause, anatomic site of injury, tbi severity, clinical findings and ct scan findin...

the brain edema is one of remarkable injuries after traumatic brain injuries (tbi). the common treatments for limiting edema are included mannitol, barbiturates, corticosteroids, hyperventilation and central nervous system derange. the most of these treatments for edema is problematic. for example, mannitol can be effective for the short period of time (24 hours) after brain injuries but is not...

Traumatic brain injury (TBI) is a major cause of morbidity and mortality in children. After TBI, the vulnerable to additional injuries (secondary injuries) because disrupts normal autoregulatory defense mechanisms. These secondary play crucial role patient prognosis. Posttraumatic seizures are an important leading further damage injured brain. Continuous monitoring by electroencephalography (EE...

Background & Aims: Release of proinflammatory cytokines after traumatic brain injury (TBI) is a major cause of brain edema. Previous studies demonstrated that sex steroids decrease brain edema induced by TBI. In this study changes of brain cytokines after the administration of estrogen and progesterone 24 hours after TBI were evaluated. Materials and Methods: Female rats were divided into 7 gro...

A traumatic brain injury (TBI) is an that disrupts the normal function, and caused by a bump, blow, or jolt to head penetrating injury. TBI range from mild concussions, without loss of consciousness, severe TBI, which can result in deep coma death. Types TBI's patients sustain include hematomas, CTE. The length time have symptoms depends on severity, with lasting few days even rest patient’s li...

Abstract Date Presented 04/21/2023 This study investigates the impact of self-regulation on reengagement in leisure activities with adults traumatic brain injury (TBI). Reengagement significantly decreases after TBI, apathy being a significant predictor this outcome. Primary Author and Speaker: Amanda Gahlot Contributing Authors: Denise Krch, Yael Goverover

Traumatic brain injury (TBI) continues to be a major contributor morbidity, disability, and mortality in all age groups. Initial damage is accompanied by acute irreversible primary the parenchyma, while subsequent secondary often progresses slowly over months years, thus providing window for therapeutic intervention. The most frequent case which happened excessive oxidative stress calcium relea...