BACKGROUND In the changing world of clinicopathologic practice where surgeons and pathologists are faced with increasing therapeutic demands, precise demands of each group from the other have often been reduced to blames and counter-blames. This study is thus aimed at auditing the current practice of specimen handling as a means of highlighting areas where mutual best practice is required. MA...

OBJECTIVE To date, there are only few systematic reports on the quality of DNA extracted from routine diagnostic cytologic specimens. It was the aim of the present study to evaluate the ability of 50% ethanol/2% carbowax (Saccomanno fixative) to preserve bronchial secretions with high quality genomic DNA as well as to compare different DNA extraction methods. METHODS DNA was extracted from 45...

The importance of fixatives in the study of internal structures of bacteria is evidenced in papers by Murray (1953), Cassel and Hutchinson (1955), and by Robinow (1956b). The primary purpose of the use of these substances is to maintain, without distortion, the structure and material in the site in the cell where it functioned. In addition, the fixative may in some cases bring about changes in ...

The goal of fixation is to rapidly and uniformly preserve tissue in a life-like state. While placing tissue directly in fixative works well for small pieces of tissue, larger specimens like the intact brain pose a problem for immersion fixation because the fixative does not reach all regions of the tissue at the same rate (5,7). Often, changes in response to hypoxia begin before the tissue can ...

The article presents the research results of effectiveness sunflower polysaccharide extract use as a feed pellets fixative and compound ingredient that improves it's nutritional taste value. studied optimal dose introduction into fattening pigs diet was scientifically substantiated. impact feeding containing new product in combination with whey on feeds digestibility, hematological, biochemical...

Histopathology is the most useful tool for diagnosis of a number of diseases, especially cancer. To be effective, histopathology requires that tissues be fixed prior to processing. Formalin is currently the most common histologic fixative, offering many advantages: it is cheap, readily available, and pathologists are routinely trained to examine tissues fixed in formalin. However, formalin fixa...

Animals communicating via scent often deposit composite signals that incorporate odorants from multiple sources; however, the function of mixing chemical signals remains understudied. We tested both a 'multiple-messages' and a 'fixative' hypothesis of composite olfactory signalling, which, respectively, posit that mixing scents functions to increase information content or prolong signal longevi...