We examined the effect on the Syrian hamster fetal pancrease of N-nitrosobis(2-oxopropyl)amine (BOP), a potent pancreatic carcinogen in adult hamsters. Pregnant Syrian hamsters (F0 generation) were treated with BOP (10 mg/kg body weight) at the 8th, 10th, 12th, and 14th days of gestation (for a total dose of 40 mg/kg body weight). Treatment was well tolerated and all hamsters delivered, at term...

BACKGROUND Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury. We have recently demonstrated that blast-triggered complement activation and cytokine release are associated with BINT. Here, we evaluated if administration of ...

Abstract Bottom of the Pyramid (BOP) populations often lack access to products and markets that would allow progress toward sustainable development goals (SDGs) (Prahalad & Hart, Strategy + Business , 2002, 26 1). Recognizing fundamental role logistics/supply chain management (LSCM) in providing such access, we review 84 case studies initiatives targeted at BOP. Surprisingly, find LSCM has ...

Both light and temperature have dramatic effects on plant development. Phytochrome photoreceptors regulate plant responses to the environment in large part by controlling the abundance of PHYTOCHROME INTERACTING FACTOR (PIF) transcription factors. However, the molecular determinants of this essential signaling mechanism still remain largely unknown. Here, we present evidence that the BLADE-ON-P...

The Board of Publications (BOP) Best Paper Award is given to a paper published in Toxicological Sciences from the July issue of the previous year through the June issue of the calendar year preceding the Annual Meeting at which the award is presented. The Editor-in-Chief and 2 Associate Editors review all papers from that time period and nominate papers for consideration. The Associate Editors ...

Te le u se @ B O P 4 Abstract: This paper considers a unique proposition; that given the evidence of women, with little access to formal finance, have been found to be much better at managing micro-enterprises and repayment when given the opportunity of microfinance at the emerging Asian bottom of the pyramid (BOP), whether the use of mobile phones and more-than-voice services could be used to ...