The hypothesis that the demineralisation associated with gonadal dysgenesis is analogous to post-menopausal osteoporosis was investigated. Bone mineral content of the distal forearm was measured in 11 adult patients with Turner's syndrome aged 18 to 57 years. As a group these patients were significantly demineralised (p less than 0.001) when compared with normal subjects. A bimodal distribution...

objective: to determine the prevalence of fractures and associated risk factors in healthy iranian children and adolescents. methods: in this cross sectional population based study, 478 healthy iranian children and adolescents aged 9–18 years old participated. baseline data and bone mineral content and density have been determined. one questionnaire was completed for all individuals including p...

Consumption of green tea may reduce body weight gain. Although many disorders are related to obesity, bone mass is positively correlated with body mass. Therefore, our purpose in this study was to determine the effects of green tea extract (GTE) on bone mass and architecture in rapidly growing lean [C57BL/6 wild type (WT)] and genetically obese, leptin-deficient (ob/ob) male mice. Five-week-old...

Fourteen preterm infants who developed bronchopulmonary dysplasia diagnosed radiologically were compared with a group of similar infants who did not. The two groups were of comparable maturity and birth weight. The clinical histories indicated that those infants with bronchopulmonary dysplasia had had longer periods of supplemental oxygen, more frequent treatment with dexamethasone, and a highe...

BACKGROUND Evidence indicates that intrauterine skeletal development has implications for bone mass in later life and that maternal fat stores in pregnancy are important for fetal bone mineral accrual. OBJECTIVE We investigated whether childhood bone mass is influenced by maternal body mass index (BMI) via an intrauterine mechanism by comparing parental associations. DESIGN We conducted a m...

The purpose of this study was to determine the influence of preterm low birth weight on bone mineral content in adolescence. In 2007 to 2008, data on adolescents were obtained for study, including 16 females and 25 males who were born preterm (≤37 weeks' gestation) between October 1, 1989, and December 31, 1995, with a birth weight of less than 1850 g. Preterm low-birth-weight individuals were ...

The aim of this contribution is to provide reference data for peripheral quantitative computed tomography (Stratec XCT2000) performed at the proximal radius (the so-called '65% site') of young subjects and to discuss the interpretation of such analyses. Data from a previous reference data study on 469 subjects between 6 and 40 years were re-analyzed and smooth curves were fitted. The correspond...

The genetic bases of peak bone mass determinants are still poorly understood, particularly in males. We investigated the relationship between vitamin D receptor (VDR) 3'- and 5'-gene polymorphisms (as determined by the restriction enzymes BsmI and FokI) and bone mineral mass, and calcium and inorganic phosphate (Pi) metabolism in an homogeneous cohort of young healthy men. In 104 healthy subjec...