1) Background: The complement becomes a major link between infection and inflammatory pathology including periodontitis. Gingipians as important virulence factors of P. gingivalis have the activity of C5 convertase, could cleave C5 into fully functional C5a to activate C5aR. The above process could be blocked by the C5aR antagonist (PMX-53) to suppress periodontal inflammation, and then achieve...

This study aims to determine the antioxidant, protein, and fat content of chicken nuggets through addition goat skin bone gelatin which was previously pretreated with Lactobacillus plantarum 1UHCC acetic acid. Data were processed using a completely randomized design (CRD) tested further Duncan's test treatments including pretreatment (CGSP), acid (CGSA), Plantarum (CGBP), (CGBA) control (withou...

introduction: osseous tissue developes via either endochondral (ec) or intramemberanous (im) ossification. the bone matrix gelatin (bmg) from both developmental types can induce bone formation when implanted in the muscle of the rat. in this research, the resorption of im-bmg particles, inductivity of im-bmg and the nature of heterotropic calcification was evaluated at implantation site. materi...

The uses of shark collagen as a matrix for cell culture and as a substrate for zymography were investigated. Fibroblasts were cultured on a gel matrix of shark type I collagen at 30 degrees C. The collagen gel had contracted by 4 days of incubation. Individual fibroblasts were visible against the transparent background of the contracted collagen as long, lean star-shaped cells. The matrix metal...

Controlled release drug delivery systems are well established as oral and implantable dosage forms. However, the controlled release paradigm can also be used to present complex soluble signals responsible for cellular organization during development. Endochondral ossification (EO), the developmental process of bone formation from a cartilage matrix is controlled by several soluble signals with ...

The use of bioscaffolds for tissue repair is widely accepted. They can provide structural stability and a 3D system on which cells can grow new tissue. Natural bone is composed of organic (mainly collagen) and mineral biomaterials (predominantly carbonate hydroxyapatite, HA). In recent years, developments in 3D porous-scaffold manufacturing have increased hopes of successful fabrication of stru...