نتایج جستجو برای: bms

تعداد نتایج: 3926  

Journal: :Antimicrobial agents and chemotherapy 2012
Beata Nowicka-Sans Yi-Fei Gong Brian McAuliffe Ira Dicker Hsu-Tso Ho Nannan Zhou Betsy Eggers Pin-Fang Lin Neelanjana Ray Megan Wind-Rotolo Li Zhu Antara Majumdar David Stock Max Lataillade George J Hanna John D Matiskella Yasutsugu Ueda Tao Wang John F Kadow Nicholas A Meanwell Mark Krystal

BMS-663068 is the phosphonooxymethyl prodrug of BMS-626529, a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells. The activity of BMS-626529 is virus dependent, due to heterogeneity within gp120. In order to better understand the anti-HIV-1 spectrum of BMS-626529 against HIV-1, in vitro activities against a wide variety of laboratory st...

Journal: :Internal medicine 2008
Nobuo Shiode Kinya Shirota Kenji Goto Akinori Sairaku Shinya Mikami Yasuko Kato Kazuyoshi Suenari Hiroshige Ishi

BACKGROUND The sirolimus-eluting stent (SES) has dramatically reduced the rate of restenosis in comparison to that with the bare-metal stent (BMS). In previous studies, the minimal luminal diameter (MLD) of lesions treated with a BMS was shown to improve from 6 months to 1 year. METHODS To evaluate 6-month and 1-year outcomes, angiographic follow-up data were analyzed for 285 patients (451 le...

2016
Robert Zivadinov Diane L. Cookfair Lauren Krupp Aaron E. Miller Neil Lava Patricia K. Coyle Andrew D. Goodman Burk Jubelt Michael Lenihan Joseph Herbert Malcolm Gottesman David H. Snyder Brian R. Apatoff Barbara E. Teter Allan B. Perel Frederick Munschauer Bianca Weinstock-Guttman

BACKGROUND This retrospective analysis explored prognostic factors associated with a benign multiple sclerosis (BMS) disease course at baseline and over the 4-year follow-up. METHODS Patients from the centralized New York State Multiple Sclerosis Consortium registry were classified as having BMS according to 3 different criteria centered on disease duration and disability. Additional analyses...

Journal: :Current Biology 2017
Ranjay Jayadev David R. Sherwood

Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues. Their sheet-like structure derives from two independent polymeric networks - one of laminin and one o...

2017
Zhenghong Zihua zhu Guoweijian Zhangning Caiyunyun Yingjiangshan Xiaomi

Background We explored risk factors for bone metastasis (BMs) in colorectal cancer (CRC) to improve in early diagnosis and follow-up and to reduce bone metastasis. Methods With a retrospective analysis of 2066 patients with CRC treated in our institution from January 2006 to January 2015, we assessed high-risk variables associated with bone metastasis using univariate and multivariate analyse...

Journal: :Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2014
Jan B Pietzsch Benjamin P Geisler Abigail M Garner Thomas Zeller Michael R Jaff

OBJECTIVES To study the economic impact on payers and providers of the four main endovascular strategies for the treatment of infrainguinal peripheral artery disease. BACKGROUND Bare metal stents (BMS), drug-eluting stents (DES), and drug-coated balloons (DCB) are associated with lower target lesion revascularization (TLR) probabilities than percutaneous transluminal angioplasty (PTA), but th...

2013
Judith H. Waknine-Grinberg Simcha Even-Chen Jasmine Avichzer Keren Turjeman Annael Bentura-Marciano Richard K. Haynes Lola Weiss Nahum Allon Haim Ovadia Jacob Golenser Yechezkel Barenholz

Cerebral malaria is the most severe complication of Plasmodium falciparum infection, and a leading cause of death in children under the age of five in malaria-endemic areas. We report high therapeutic efficacy of a novel formulation of liposome-encapsulated water-soluble glucocorticoid prodrugs, and in particular β-methasone hemisuccinate (BMS), for treatment of experimental cerebral malaria (E...

Journal: :Journal of the American College of Cardiology 2011
Gaku Nakazawa Fumiyuki Otsuka Masataka Nakano Marc Vorpahl Saami K Yazdani Elena Ladich Frank D Kolodgie Aloke V Finn Renu Virmani

OBJECTIVES Human coronary bare-metal stents (BMS) and drug-eluting stents (DES) from autopsy cases with implant duration >30 days were examined for the presence of neointimal atherosclerotic disease. BACKGROUND Neointimal atherosclerotic change (neoatherosclerosis) after BMS implantation is rarely reported and usually occurs beyond 5 years. The incidence of neoatherosclerosis after DES implan...

Journal: :Circulation. Cardiovascular interventions 2016
Daisuke Nakamura Guilherme F Attizzani Catalin Toma Tej Sheth Wei Wang Mohamad Soud Reem Aoun Ramyashree Tummala Milana Leygerman Anas Fares Emile Mehanna Setsu Nishino Anthony Fung Marco A Costa Hiram G Bezerra

BACKGROUND There are few clinical studies on the pathophysiological mechanisms of very late stent thrombosis (VLST). We report optical coherence tomography findings in patients with VLST and compare the findings between bare-metal stents (BMS) and drug-eluting stents (DES). METHODS AND RESULTS We conducted a registry of stent thrombosis at 4 North American centers with optical coherence tomog...

2017
Osamu FUKUDA Iqbal AHMED Daisuke HASHIMOTO

To estimate more accurately the beef marbling score (BMS) of live beef cattle, the Bayesian network model (BNM) could be used in parallel with other developed methods, such as ultrasound (US) image analysis with a neural network (NN), biological impedance analysis (BIA) and visual inspections of an experienced inspector. Additionally, most of these methods individually represents positive trend...

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