A related slide show is available at www.nejm.org n examination of the blood smear (or film) may be requested by physicians or initiated by laboratory staff. With the development of sophisticated automated blood-cell analyzers, the proportion of blood-count samples that require a blood smear has steadily diminished and in many clinical settings is now 10 to 15 percent or less. Nevertheless, the...

The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by an ellipsoid form, an ellipse detector algorithm may be successfully applied in order to recognize them. This paper presents an algorithm for the automatic ...

An acoustic/photoacoustic microscope was used to create micrometer resolution images of stained cells from a blood smear. Pulse echo ultrasound images were made using a 1000 MHz transducer with 1 μm resolution. Photoacoustic images were made using a fiber coupled 532 nm laser, where energy losses through stimulated Raman scattering enabled output wavelengths from 532 nm to 620 nm. The laser was...

Classification and counting of cells in the blood is crucial for diagnosing treating diseases clinic. A peripheral smear method a fast, reliable, robust diagnostic tool examining samples. However, cell overlap during process may cause incorrectly predicted results classifying types. The overlapping problem can occur automated systems manual inspections by experts. Convolutional neural networks ...