BACKGROUND 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a long half-life of 5-10 years in human beings as a result of its high lipophilicity, and little or no metabolism. We monitored TCDD, its form, distribution, and elimination in Victor Yushchenko after he presented with severe poisoning. METHODS In late December, 2004, a patient presented with TCDD poisoning; the levels in his blood ser...

This study was conducted to evaluate the effects of dietary inclusion of thyme essential oil (TEO) on growth performance and immune responses of broiler chicks subjected to heat stress (HS). Broilers were divided into five groups; group 1) chicks fed with basal diet and reared under thermoneutral condition; group 2) chicks fed with basal diet and subjected to HS condition; and groups 3, 4 and 5...

seventy six high and low producer cows were selected to determine the composition of theblood and milk parameters, and their interrelationships to determine the indices which could beuseful to improve the milk yield. the highest mean blood concentrations were found in highproducer cows. mean values for blood urea nitrogen (bun), serum protein (sptn), creatinine,triglycerides (tgs), cholesterol,...

the aim of this study was to compare the effects of two levels of crude protein using poultry by-product meals (pbpm) fed during late gestation on the performance, blood metabolites, and colostrum composition of holstein dairy cows. sixteen multiparous cows 26±6 d before expected calving were assigned randomly to two treatments containing 1) 14% and 2) 16% crude protein. the cow’s bcs was 3.56 ...

Diabetes mellitus (DM) is a worldwide disease characterized by metabolic disturbances, frequently associated with high risk of atherosclerosis and renal and nervous system damage. Here, we assessed whether metabolites reflecting oxidative redox state, arginine and nitric oxide metabolism, are differentially distributed between serum and red blood cells (RBC), and whether significant metabolism ...

Growth in world population will inevitably leads to increased demand for protein for humans and animals. Protein from insects and blood plasma are being considered as possible alternatives, but more research on their nutritional quality and health effects is needed. Here, we studied the effect of dietary protein source on metabolism and metabolic amine profiles in serum and urine of mice. Group...

INTRODUCTION AND OBJECTIVE Mast cells (MC) are effector cells during severe systemic reactions (SR) to Hymenoptera stings. Venom specific immunotherapy (VIT) is the treatment of choice for prevention of SR to stings. Tryptase and prostaglandin D₂ metabolites (PGD₂) are the markers of MC activation. The study design was to 1. compare baseline values of serum tryptase concentration (BST) and PGD₂...

BACKGROUND Changes in tryptophan metabolism through the vitamin B-6-dependent kynurenine pathway have been linked to activation of the immune system. OBJECTIVE We hypothesized that blood concentrations of tryptophan and its catabolites were associated with biomarkers relevant to inflammatory processes in healthy noninflamed subjects. METHODS Healthy young adults (n = 737) aged 18-28 y witho...

Metabolomics, the systematic investigation of metabolites in biological fluids, cells or tissues, reveals essential information about metabolism and diseases. Metabolites have functional roles myriads processes, as substrates products enzymatic reactions, but also cofactors regulators large numbers biochemical mechanisms. These functions involve interactions with macromolecules. Yet, methods to...