conclusions rotem can be used to detect postoperative hemostatic changes following cardiac surgery appropriately and can be useful to choose suitable blood products that may reduce the need for blood transfusion, contributing to better patient blood management. background coagulopathy after cardiopulmonary bypass (cpb) may lead to increased morbidity and mortality. routine conventional coagulat...

Bleeding disorders are usually taken to mean coagulopathies with reduced clotting of the blood but also encompass disorders characterised by abnormal platelet function or blood vessel walls that result in increased bleeding. Bleeding disorders may result from faults at many different levels in the coagulation process. They can range from severe and life-threatening conditions, such as haemophil...

Infertility is a common problem that affects many couples worldwide, with an estimated 48.5 million experiencing infertility. The causes of infertility are diverse and complex, combination genetic, environmental, lifestyle factors contributing to the problem. While reproductive medicine has advanced significantly in recent years, diagnosis treatment remains challenge, particularly cases where c...

BACKGROUND Transfusion therapy is associated with increased morbidity, mortality and costs. Conventional coagulation tests (CCT) are weak bleeding predictors, poorly reflecting coagulation in vivo. Thromboelastometry (ROTEM) provides early identification of coagulation disorders and can guide transfusion therapy by goals, reducing blood components transfusion. OBJECTIVE The aim of this study ...

OBJECTIVE To assess potential diagnostic and practice barriers to successful management of massive postpartum hemorrhage (PPH), emphasizing recognition and management of contributing coagulation disorders. STUDY DESIGN A quantitative survey was conducted to assess practice patterns of US obstetrician-gynecologists in managing massive PPH, including assessment of coagulation. RESULTS Nearly ...

the mean percentage of cryptogenic strokes among ischemic strokes is 31%, of which one-third may be associated with patent foramen ovale. the foramen ovale is required for blood flow through the fetal atrial septum.  it is formed as of the fourth week of gestation, and this leads to right-left interatrial shunt that allows the passage of oxygenated blood to systemic circulation. in 75% of cases...

PURPOSE OF REVIEW An update on recent developments in diagnosis and treatment of disseminated intravascular coagulation. RECENT FINDINGS Disseminated intravascular coagulation is defined as a typical disease condition with laboratory findings indicating massive coagulation activation and reduction in procoagulant capacity. Clinical syndromes associated with the condition are consumption coagu...

Blood platelets are the central players in thrombosis and blood coagulation. Moreover, they also exhibit immunoregulatory properties bridge hemostasis immunity. Morphological functional characteristics of ensure continuous surveillance for vascular system, recognition different hazards, development appropriate response recruitment immune cells. Indirect platelet-leukocyte interactions mediated ...

Dental practitioners must be well informed about the pathology, complications and treatment options associated with bleeding disorders patients. Prolongation of time can seriously complicate patient’s condition during after surgery, especially if there is iron deficiency anemia or any other accompanied by a decrease in hematopoiesis. For this reason, dentist surgeon aware presence such diseases...