نتایج جستجو برای: blood cancer
تعداد نتایج: 1553562 فیلتر نتایج به سال:
Background: It is reported that high frequency of chromosomal aberrations in peripheral blood lymphocytes of individuals is a marker of cancer predisposition. The aim of this study was to investigate the in vitro frequency of chromosomal damage in lymphocytes of patients with head and neck cancer against gamma irradiation compared with those in healthy individuals. Methods: In a case and con...
nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...
background: alteration in peripheral blood lymphocytes (pbls) is usually investigated to provide an evidence of the host immune responses to tumor antigens. the tumor infiltrating nk cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. objective: to analyze peripheral blood and tumor associated natural killer (nk) cells in patients with breast ca...
Lung cancer is among the most common cause of cancer death in the world. Since the disease is diagnosed in the middle or late stages of the cancer development a more efficient method for an early diagnosis of the disease is required. The main goal of this study was to investigate the correlation between aberrant promoter methylation of the two genes: SHOX2(Short stature homeobox 2) and WT1(Wilm...
Background: By binding SHBG hormone to sex hormones, in addition to carrying them in the blood, they regulate the amount of tissue availability. Since the genetic changes in the structure of globulin affect it’s binding to hormones, so in this study the effects of single nucleotide change in exon 8 or rs 6259 in the incidence of prostate cancer is evaluated. Methods: The study populati...
ABSTRACT Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is known to play a key role in the initiation, growth and...
Background: Blood stream infection is one of the main causes of morbidity and mortality in patients with cancer. The purpose of this study was to evaluate the prevalence of aerobic and anaerobic-bacteremia in hospital inpatients with cancer and to determine the antibiotic resistance profile in isolated organisms in Kerman, southeast Iran. Methods: Total of 240 blood cultures from 136 patients w...
Background: Quantification of radiation-induced apoptosis in peripheral blood lymphocytes (PBLs) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. Materials and Methods: The neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation ...
background: invasive ductal carcinoma is the most common type of breast cancer in iran. impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood. it is believed that infiltrated immune cells, especially macrophages, may provide help for tumor cell growth and metastasis. objective: to analyze the status of tumor as...
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