This report details our experience with documented chronic second-degree atrioventricular (AV) nodal block (proximal to His [H]) in 56 patients. Forty-six men (82%) and 10 women (18%), ages 18-87 years, were studied. Nineteen of the patients (34%) had no organic heart disease (including seven trained athletes) and 37 (66%) had organic heart disease. ECGs in all patients demonstrated episodes of...

The aim of this study was to examine the birthdates distribution of French male soccer players (n = 363,590) who dropped out during or after the 2006-2007 season, to determine whether the relative age effect is linked to dropout behaviour. An over-representation of players born late in the competitive year was observed among dropouts, from the U-9 to the U-18 age categories, whereas their count...

BACKGROUND AND OBJECTIVES Unilateral spinal anesthesia may be advantageous, especially in the outpatient setting. Low local anesthetic doses, slow spinal injection rate and the lateral position have been related to the easiness of inducing unilateral spinal anesthesia. This study aimed at investigating the possibility of inducing unilateral spinal anesthesia with isobaric 0.5% bupivacaine. ME...

BRITTA SIEGMUND,1 GIAMILA FANTUZZI,1 FLORIAN RIEDER,2 FABIA GAMBONI-ROBERTSON,3 HANS-ANTON LEHR,4 GUNTHER HARTMANN,2 CHARLES A. DINARELLO,1 STEFAN ENDRES,2 AND ANDREAS EIGLER2 Departments of 1Medicine and 3Surgery, University of Colorado Health Sciences Center, Denver, Colorado 80206; 2Division of Clinical Pharmacology, Medizinische Klinik Innenstadt, Klinikum of the Ludwig-Maximilians-Universi...

1. Adrenocorticotropin (ACTH)-induced steroidogenesis, obtained by continuous administration of ACTH for 3 days, produces in man (a) sustained elevations of plasma deoxycorticosterone and cortisol concentrations, (b) transient elevations of plasma aldosterone and 18-hydroxycorticosterone concentrations that return to near-control values, and (c) brisk initial increases in plasma 18-hydroxydeoxy...

2,4-dithiouracil (DTU) forms in the crystals the H-bonded monohydrates of a 1:1:1 ratio with 18-crown-6 (18C6) 1, cis,syn,cis-isomer of dicyclohexano-18-crown-6 (DCH6A) 2, and benzo-18-crown-6 (B18C6) 3, while the anhydrous adduct with cis,anti,cis-isomer of dicyclohexano-18-crown-6 (DCH6B) 4 is of a 2:1 ratio. In 1-3 the components reproducibly alternate in the chains, while in 4 the chains ar...

PURPOSE To assess the extent of osseointegration with rough-surface implants and new bone formation (NBF) within human freeze-dried bone blocks (h-FDB) grafted over rabbit calvaria. MATERIALS AND METHODS A total of 18 rectangular h-FDB blocks were stabilized bilaterally to the calvaria of nine New Zealand rabbits by two mini titanium screws each. A total of 18 rough-surface implants (5.0 × 6....

OBJECTIVES We prospectively evaluated the mechanism of syncope in patients with positive adenosine triphosphate (ATP) tests (defined as the induction of atrioventricular [AV] block with a ventricular pause >/=6 s after an intravenous bolus of 20 mg ATP). BACKGROUND Patients with unexplained syncope tend to have more positive ATP tests results than those without syncope. METHODS An implantab...

AIMS The objective of this prospective study was to assess risk factors for the development of atrioventricular block following slow pathway modification in patients with atrioventricular nodal reentrant tachycardia and a pre-existing prolonged PR interval. METHODS AND RESULTS Of 346 consecutive patients with atrioventricular nodal reentrant tachycardia undergoing slow pathway modification, 1...

BACKGROUND AND OBJECTIVES Hemorrhoidectomy may be performed under several anesthetic techniques and in outpatient regimen. Postoperative pain is severe and may delay discharge. This study aimed at evaluating bilateral pundendal nerves block for post- hemorrhoidectomy analgesia. METHODS Bilateral pundendal nerves block with 0.25% S75:R25 bupivacaine was performed with nerve stimulator in 35 pa...