Oritavancin is a novel glycopeptide currently being developed for the treatment of complicated skin and skin structure infections (cSSSI), including those caused by multidrug resistant gram-positive pathogens. The disposition of oritavancin in skin structures was investigated using a cantharide-induced blister fluid model. Seventeen healthy male subjects received oritavancin, but only 16 subjec...

A checklist of 29 brachypterous species in the tenebrionid tribe Stenochiini is given for China and neighboring countries. A new species is described and illustrated under the name of Strongylium liangi sp. n. (CHINA: Yunnan). Also, some new distribution data is provided for S. claudum (Gebien, 1914), and a distribution map of all Strongylium species in the checklist is presented.

Ulomimus indicus Bates, 1873 of the tribe Ulomini is recorded for the first time from China (Guangxi and Hainan), Indonesia (Sumatra) and Thailand (Chiang Dao). A redescription of the male and the first description of the female are also provided.

Three species of the genus Xenocerogria Merkl, 2007 have been recorded in China, Xenocerogriafeai (Borchmann, 1911), Xenocerogriaignota (Borchmann, 1941) and Xenocerogriaruficollis (Borchmann, 1912). Xenoceraxanthisma Chen, 2002 is proposed as a junior synonym of Xenocerogriaruficollis. Lectotype of Xenocerogriaignota is designated, and the species is transferred to the genus Lagria Fabricius, ...

A new species, Nalassus (Helopocerodes) olgae sp. n., is described from Primorsky Krai in the Russian Far East. A new combination is established: Nalassus (Helopocerodes) magyari (Kaszab, 1968), comb. n. The new species is similar to N. magyari but differs in the sculpture of the metaventrite, larger body and widely flattened lateral sides of the pronotum.

Cantharidin, a toxic monoterpene secreted by blister beetles, has long been used in traditional Chinese and modern medicine for its unique properties. However, despite widespread use, effects on fish have not studied. The aim of this study was to evaluate the potential therapeutic applications cantharidin examining antioxidant, hemagglutinating, hemolytic, cytotoxic activities at different conc...

A new species, Hedyphanes chikatunovi sp. n., is described from southern Israel (Negev, Gerofit) and Egypt (Northern Sinai). These localities represent the southwestern limit of the distribution of the genus. The new species is placed in a new monotypic subgenus, Microhedyphanes subgen. n.

BACKGROUND AND PURPOSE Blister aneurysms of the supraclinoid ICA represent a rare but potentially catastrophic cause of SAH, often presenting both diagnostic and therapeutic dilemmas. We explore the utility of CTA in the identification and characterization of ICA blister aneurysms. MATERIALS AND METHODS We performed a retrospective review of catheter cerebral angiograms obtained at our instit...

Bullous pemphigoid (BP) is an autoimmune blistering skin disease that is more common in elderly individuals. The aim of this study was to determine the functional activity of eosinophils in patients with BP compared with healthy donors. Blood, skin and blister-derived eosinophils were strongly activated in patients with BP, seen by increased surface expression of CD69 compared with controls. CD...