Full blood count and erythrocyte sedimentation rate, antistreptolysin titre, albumin/ globulin ratio, blood sugar estimation, gonococcal complement-fixation test, Wassermann and Treponema pallidum immobilization tests, Waaler-Rose latex-fixation test, Toxoplasma complement-fixation test, Tine test, histoplasmosis complement-fixation test. Urine and stool examination for parasites and bacteria. ...

An 82-year-old man presented with high-grade fever, left flank pain with dysuria. Urine culture revealed the growth of Escherichia coli. Contrast-enhanced computed tomography features were suggestive of xanthogranulomatous pyelonephritis (XPN) of the left kidney. Serial hemogram studies revealed markedly raised white cell count with the presence of blast cells. On further evaluation by peripher...

Life-threatening hypophosphataemia developed in a 47 year old woman with blastic crisis of chronic myelogenous leukaemia. The patient's hospitalization was characterized by reciprocal relationship between her white cell count and the serum phosphorus levels. The patient did not demonstrate any of the usual causes of profound hypophosphataemia. The postulated mechanism of this patient's hypophos...

The efficacy of azacitidine has been demonstrated in acute myeloid leukemia (AML) patients with 20-30% bone marrow (BM) blasts, but limited data is available on patients with ≥30% blasts. We analyzed 55 newly diagnosed AML patients, treated with azacitidine. The overall response rate was 42%. Median overall survival (OS) was 12.3 months. We confirmed poor-risk cytogenetics, therapy-related AML,...

purpose : to assess and to compare stromal and endothelial changes at the cellular level in patients who had photorefractive keratectomy (prk) and laser in situ keratomileusis (lasik) using in vivo confocal microscopy methods : in this semiexperimental study, 32 eyes of 16 patients (4 males and 12 females) with low to moderate myopia [-1.00 to -4.50 diopters (d)] or low to moderate myopic astig...

In 1999 a working group of the World Health Organization (WHO) published a revised classification for myelodysplastic syndromes (MDS): RA, RARS, refractory cytopenia with multilineage dysplasia (RC+Dys), RAEB I and II, del (5q) syndrome, and MDS unclassifiable. Chronic myelomonocytic leukemia (CMML) and RAEB-t were excluded. Standard French-American-British (FAB) and new WHO classifications hav...

A 72-year-old man presented with a 1-month history of lymphadenopathy. He was admitted to our hospital in May 2016. A complete blood count upon admission showed the following findings: hemoglobin, 13.0 g/dL; platelet count, 84×10/L; and white blood cell count, 6.3×10/L. His laboratory test showed increased lactate dehydrogenase (2,382 U/ L). Computed tomography showed a small pulmonary nodule (...

Embryonic stem cell-derived embryoid bodies contain a unique precursor population which, in response to vascular endothelial growth factor, gives rise to blast colonies in semi-solid medium. Upon transfer to liquid culture with appropriate cytokines, these blast colonies generate both hematopoietic and adherent, stromal-type cells. Cells within the adherent population display characteristics of...

When spleen cells of 5-fluorouracil (5-FU)-treated mice were cultured in the presence of interleukin 3 (IL-3), most colonies revealed IL-3 concentration-dependent colony formation except for mast cell colonies and blast cell colonies. While most colonies were smaller in lower concentrations of IL-3, the size of the blast cell colonies were similar between high and low IL-3 groups. These data su...