Prostate cancer typically develops later in life. Hence, identi‐ fying the botanical compounds that can prevent or delay disease progression may have a positive effect on the quality of life and reduce the healthcare costs of the aging population.[1] Supporting the statement, it could be accepted that the burden of increasing morbidity and mortality due to prostate cancer imposes a need for new...

Eleostearic acid (alpha-ESA) is a conjugated linolenic acid that makes up approximately 60% of Momordica charantia (bitter melon) seed oil. Prior work found that water extract from bitter melon was able to inhibit breast cancer. Here, we investigated effects of alpha-ESA on both estrogen receptor (ER)-negative MDA-MB-231 (MDA-wt) and ER-positive MDA-ERalpha7 human breast cancer cells. We found ...

Buah pare (Momordica charantia L.) merupakan tanaman yang memiliki bau khas dimanfaatkan oleh masyarakat sebagai sayuran dan untuk pengobatan tradisional seperti batuk berdahak disentri. kandungan senyawa alkaloid, flavonoid, saponin, tannin, triterpenoid dapat aktivitas antibakteri. Penelitian ini bertujuan menentukan antibakteri berdasarkan diameter zona hambat ekstrak buah terhadap Vibrio ch...

We sought to evaluate the effects of Momordica charantia (bitter melon, BM) extract on insulin sensitivity, NAFLD, hepatic FGF21 and AMPK signaling in mice fed a high-fat diet. Male C57/B6 mice were randomly divided into HFD and HFD supplementation with BM for 12 week. Body weight, plasma glucose, FGF21 and insulin levels, hepatic FGF21 and AMPK signaling proteins were measured. The results sho...