نتایج جستجو برای: biopharmaceutical
تعداد نتایج: 1766 فیلتر نتایج به سال:
Several new pyrazole derivatives have demonstrated promising antiproliferative and cytotoxic effects, but their poor solubility raised concerns over possible biopharmaceutical limitations. In order to improve their pharmaceutical potential we performed the biopharmaceutical profiling for nine pyrazole compounds using in vitro and computational methods. The experimental solubility was determined...
As the biopharmaceutical industry evolves to include more diverse protein formats and processes, more robust control of Critical Quality Attributes (CQAs) is needed to maintain processing flexibility without compromising quality. Active control of CQAs has been demonstrated using model predictive control techniques, which allow development of processes which are robust against disturbances asso...
BACKGROUND The relatively little resistance to quinine globally has led to an increase in its use in P. falciparum malaria especially in multi-drug resistant strains. OBJECTIVE To evaluate the physicochemical and equivalency of three brands of quinine sulphate tablets available in South Western region of Nigeria. METHODS The pharmaceutical and chemical equivalence of three brands of quinine...
This article provides a summary of discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum organized by ASA BIOP Methods in Oncology ...
Abstract We investigate the determinants of University-Industry interactions in the biopharmaceutical in Italy, over the period 2004-2010. Because of the specificities of biopharmaceutical industry, we choose co-publishing as a proxy of University-Industry relations. By integrating different statistical sources, we construct a novel dataset of co-published articles containing measures of proxim...
The ability to characterize protein therapeutics throughout the product development cycle is an important requirement for analytical support in the biopharmaceutical industry. Liquid chromatography–mass spectrometry (LC–MS) has played an important role in the ensemble of analytical tools to generate in-depth characterization data for biotherapeutic drugs. All too often in biopharmaceutical char...
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