Synthetic biology and biomolecular computation are disciplines that fuse when it comes to designing and building information processing devices. In this chapter, we study several devices that are representative of this fusion. These are three gene circuits implementing logic gates, a DNA nanodevice and a biomolecular automaton. The operation of these devices is based on gene expression regulati...

Protein loop compaction and the origin of the effect of arginine and glutamic acid 1 mixtures on solubility, stability and transient oligomerization of proteins 2 3 Jascha Blobel, Ulrika Brath, Pau Bernadó, Carl Diehl, Lidia Ballester, 4 Alejandra Sornosa, Mikael Akke & Miquel Pons 5 6 1. Laboratory of Biomolecular NMR, Institute for Research in Biomedicine. Parc 7 Científic de Barcelona, Baldi...

1 Instituto de Biotecnoloǵıa, Universidad Nacional Aut. de México, AP510-3, Cuernavaca 62250, Mexico 2 European Molecular Biology Laboratory, Meyerhofstr. 1, 69117 Heidelberg, Germany 3 Max Delbrück Center for Molecular Medicine, 13092 Berlin-Buch, Germany 4 University of Heidelberg, Dept. of Parasitology, INF 324, 69120 Heidelberg, Germany 5 Nijmegen Centre for Molecular Life Sciences, p/a CMB...

Title NMR structure note : a defective isoform and its activity-improved variant of a type III antifreeze protein from Zoarces elongates Kner Author(s) Kumeta, Hiroyuki; Ogura, Kenji; Nishimiya, Yoshiyuki; Miura, Ai; Inagaki, Fuyuhiko; Tsuda, Sakae Citation Journal of Biomolecular NMR, 55(2): 225-230 Issue Date 2013-02 Doc URL http://hdl.handle.net/2115/52207 Right The final publication is avai...

Measuring the nuclear magnetic resonance spectra of low-gamma heteronuclei such as 15N constitutes an important analytical tool for the characterization of molecular structure and dynamics. The reduced resonance frequencies and magnetic moments of these heteronuclei, however, make the sensitivity of this kind of spectroscopy inherently lower than that of comparable H NMR observations. A well-kn...

We have assessed the potential of an alternative probe tuning strategy based on the spin-noise response for application in common high-resolution multi-dimensional biomolecular NMR experiments with water signal suppression on aqueous and salty samples. The method requires the adjustment of the optimal tuning condition, which may be offset by several 100 kHz from the conventional tuning settings...

Artificial Biomolecular Condensates In article number 2104704, Huaimin Wang and co-workers report a general approach for constructing artificial biomolecular condensates of oligopeptide in living cells. The rationally designed aromatic-capped peptides can reversibly form nanofibrous hydrogel with change the conformation morphologies lysosome. formed undergo swelling lysosome, leading to lysosom...