pathological changes within an organ can be reflected as proteomic patterns in biological fluids such as plasma, serum, and urine. the surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (seldi-tof ms) has been used to generate proteomic profiles from biological fluids. mass spectrometry yields redundant noisy data that the most data points are irrelevant features ...

Introduction: Climate change and hot processes in the workplaces has led to an increase in the effects of heat stress on employed people, which has become a major concern, especially in tropical and subtropical countries. Early detection of biomarkers in induction of heat stress-related DNA damage can be used in the identification and evaluation of health and safety, including occupational heal...

Objective: Inflammation along with oxidative stress plays an important role in the development, progression, instability and rupture of coronary atherosclerotic plaques. Several studies introduced curcumin (diferuloylmethane) as a wonderful chemical in Curcuma longa<span style="font-size: m...

background: several changes in serum biochemical factors occur in acute myocardial infarction (ami). recently alterations in serum levels of homocysteine (hcy), sialic acid (sa) and high sensitive c-reactive protein (hs-crp) has been attended as risk factors and index for prediction. this study was aimed to show the alterations in these factors and their relationships in ami. methods: thirty fo...

      Kawasaki disease (KD) is characterized as the leading cause of acquired cardiac disease in children. Accurate and timely diagnosis of KD is of high importance for preventing its cardiac complications. However, diagnosis merely based on clinical findings has a number of challenges and, limitations. Therefore, researchers are investigating to find more object...

Introduction: 238U decays with alpha particles emission into 234Th and the series ends with 206Pb. The unstable nucleus loses the energy with emitting ionizing alpha particles for reaching a stable state. It is undergoing alpha decay with decay energy (4.679 MeV). Alpha particles enter the human and animal bodies through inhalation of air or ingestion of contaminated food and water. This study ...

Bladder cancer is the fifth most common cancer with significant morbidity and mortality. Recently, numerous studies demonstrated that microRNAs are emerging as diagnostic biomarkers for bladder cancer. Specific miRNA profiles have been identified for several samples from patients with bladder cancer. MicroRNAs are noncoding RNA molecules of approximately 23 nucleotides that play important roles...

patients and methods this cross-sectional study included a total of 120 adult predialysis ckd patients. forty patients were allocated in each predialysis ckd group of stages 3, 4, and 5. serum ctnt and hs-crp, plasma nt-probnp, and single spot urine albumin creatinine ratio (acr) were measured. ultrasonographic examination of carotid artery was done with 7.5 mhz linear probe in b mode ultrasono...