Bioluminescence tomography (BLT) is used to localize and quantify bioluminescent sources in a small living animal. By advancing bioluminescent imaging to a tomographic framework, it helps to diagnose diseases, monitor therapies and facilitate drug development. In this paper, we establish a direct linear relationship between measured surface photon density and an unknown bioluminescence source d...

The requirement for artificial but realistic, tactile, anatomical models for surgical practice in medical simulation is increasingly evident and shows potential for greater efficiency and availability, and lower costs. Anatomically correct, detailed models with the physical surgical characteristics of real tissue, combined with the ability to reproduce one-off cases, would provide an invaluable...

Here we describe and provide diffusion magnetic resonance imaging (dMRI) data that was acquired in neural tissue and a physical phantom. Data acquired in biological tissue includes: fixed rat brain (acquired at 9.4 T) and spinal cord (acquired at 16.4 T) and in normal human brain (acquired at 3 T). This data was recently used for evaluation of diffusion kurtosis imaging (DKI) contrasts and for ...

Since the advent of high angular resolution diffusion imaging (HARDI) techniques in diffusion MRI great efforts have been taken in order to reconstruct complex white-matter structures, such as crossing, branching and kissing fibers. However, even highly sophisticated fiber tracking schemes, such as probabilistic tracking, suffer from the data’s poor signal-to-noise (SNR) ratio. In this paper we...

Partial differential equations have been successfully used for fibre tractography and for mapping connectivity indices in the brain. However, the current implementation of methods which require 3D orientation to be tracked can suffer from serious shortcomings when invariance to 3D rotation is desired. In this paper we focus on the 3D stochastic completion field and introduce a new methodology t...

Highly resolved images of defined regions of interest within extended objects were obtaind with a 1.5 T whole-bode imager and standard hardware. The high-resolution spin echo imaging sequence avoids aliasing and allows pixel resolutions down to 39 pm which are confirmed by phantom measurements. The application of the sequence to large biological objects such as, for example, an amaryllis bulb r...

A simple and fast time-domain method for localizing inclusions, fluorescent optical probes or absorbers, is presented. The method offers new possibilities for situations where complete tomographic measurements are not permitted by the examined object, for example in endoscopic examination of the human prostate or the oesophagus. Feasibility has been envisioned with a phantom study conducted on ...

introduction: poor sensitivity and poor signal to noise ratio because of low injected thallium dose and presence of scattered photons are the main problems in using thallium in scintigraphic imaging of the heart. scattered photons are the main cause of degrading the contrast and resolution in spect imaging that result in error in quantification. thallium decay is very complicated and photons ar...

To study laser tissue interaction absorption and backscattering are the key factors to find the changes in structure and dynamics of turbid media such as complex fluids and biological tissues. Here a method to select suitable wavelength for maximum interaction with a particular type of tissue/tissue phantom, and study of backscattered light intensity at chosen wavelength with respect to change ...