Evidence has shown that miR-146a is involved in carcinogenesis and a common G/C variant (rs2910164) in the pre-miR-146a gene has been found to be associated with various cancers. We investigated the potential prognostic role of miR-146a polymorphism in prostate cancer after radical prostatectomy. Seventy-two southern Chinese with prostate cancer undergoing radical prostatectomy were included in...

biochemical polymorphism study is a method of determination of genetic variation. this variability could be a basis for selection and subsequent genetic improvement in farm animals. the polymorphism in the intron 1 of chicken growth hormone (cgh) gene was investigated in the iranian native fowls by using polymerase chain reaction (pcr)-restriction fragment length polymorphism (rflp) method. the...

BACKGROUND Differences in the distribution of the MTRR rs326119 polymorphism (c.56 + 781 A > C) between patients with congenital heart disease (CHD) and controls have been described in Chinese individuals. The association is thought to be due to deregulation of homocysteine-cobalamin pathways. This has not been replicated in other populations. The primary objective of this study was to assess t...

Background and aims: We sought to examine the interaction between CRY1 genotypes low carbohydrate diet (LCD) score effect on insulin resistance, sensitivity, homeostasis model assessment of resistance (HOMA- IR) quantitative sensitivity check index (ISQUKI). Methods: This cross-sectional study was conducted with a total 228 overweight obese women. The data related anthropometric biochemical mea...

The article presents a case of poisoning with lambda-cyhalothrin, synthetic pyrethroid, in family three (2 deaths at different times the course poisoning). A from our practice is interest not only point view frequency occurrence this type poisoning, but also as an example complex diagnostic process, including analysis circumstances, clinical data and set post-mortem studies, taking into account...

OBJECTIVE To investigate protein polymorphism of the haptoglobin (Hp) and the relationship between Hp phenotypes and anthropometric or biochemical parameters in elite Korean male athletes. MATERIALS AND METHODS Serum samples were collected from 120 Korean male elite athletes. The Hp phenotypes were determined by polyacrylamide gel electrophoresis, followed by peroxidase staining. Then anthrop...

UCP-1 is suggested to have important roles for thermogenesis and energy expenditure. To elucidate whether the A-3826G polymorphism that is located in the 5' flanking region of the UCP-1 gene has roles in healthy young people, the polymorphism was genotyped among 251 young Japanese men whose mean age is 22.7 years old. We analyzed relationship between the A-3826G polymorphism and body mass index...

We describe a previously healthy patient with chronic otitis media complicated with cerebellar abscess caused by Tsukamurella tyrosinosolvens. The organism was identified based on conventional biochemical identification methods, PCR-restriction fragment length polymorphism analysis of the hsp65 gene, and 16S rRNA gene sequencing. The patient was treated successfully with debridements and prolon...

Peroxisome Proliferator Activated Receptors (PPAR) are members of the nuclear receptor superfamily of ligand activated transcription factor consisting of 3 subtypes PPARα , PPARβ and PPARγ. PPARγ plays an important role in adipocyte differentiation and it regulates lipid metabolism as well as insulin sensitivity. Of the 3 isoforms of PPARγ, PPARγ2 are expressed in adipose tissue. Genomic DNA wa...

OBJECTIVE To determine the association of TRIB3 Q84R polymorphism with metabolic syndrome (MetS) and carotid atherosclerosis. RESEARCH DESIGN AND METHODS A case-control study enrolled 513 Chinese subjects in three groups: control, MetS, and obese. The functional TRIB3 Q84R polymorphism was genotyped among subjects undergoing carotid ultrasonography. The clinical and biochemical characteristic...