most of the biological phenomena are influenced by intermolecular recognition and interaction. thus, understanding the thermodynamics of biomacromolecule ligand interaction is a very interesting area in biochemistry and biotechnology. one of the most powerful techniques to obtain precise information about the energetics of (bio) molecules binding to other biological macromolecules is isothermal...

Sets of Hamblin alternatives are often used side by side syntactic movement and variable binding. Shan (2004) shows that previous attempts at defining a Predicate Abstraction rule for variable binding while using sets of alternatives face serious problems: they overgenerate alternatives and/or are incapable of handling binding into a wh-phrase. This paper provides a solution by assuming Poesio’...

Despite extensive research both on the theoretical and practical fronts, formalising, reasoning about, implementing languages with variable binding is still a daunting endeavour – repetitive boilerplate overly complicated metatheory of capture-avoiding substitution often get in way progressing to actually interesting properties language. Existing developments offer some relief, however at expen...

The severity of SARS-CoV-2 infection is highly variable and yet the molecular basis for this effect remains elusive. One potential contribution are differences in glycosylation target human cells, particularly as has capacity to bind sialic acid which a common, variable, terminal modification glycans. viral spike glycoprotein (S) cellular receptor, angiotensin-converting enzyme 2 (ACE2) both de...

Background:Epidermal growth factor receptor (EGFR) overexpression is a characteristic of several malignancies and could be considered as an excellent target for designing specific inhibitors such as anti-EGFR monoclonal antibodies for cancer therapy. Drawbacks exerted by large sizes of full-length antibodies have lead to the development of single chain antibodies, which benefit from having smal...

variable binding identifies, for each memory read instruction of an execution trace, the program variable containing the address specifying the location from which the data should be read. Consider pseudo-code of an emulator that regularly fetches instructions pointed to by the VPC: instruction = bytecode[VPC] or instruction = ∗VPC (1) In these examples, the VPC is an index into an array of byt...

two newly-created water-soluble complexes of palladium(ii)/platinum(ii)-dithiocarbamate, [pd/pt(phen)(pyr-dtc)]no3 (phen = 1,10-phenanthroline and pyr-dtc = pyrrolidinedithiocarbamate) were synthesized. also, their chemical characteristics are reported in the current research paper. in these complexes, the dithiocarbamato ligand coordinates to pt(ii) or pd(ii) center with two sulfur atoms as bi...