Isabella Nogues, BA, Bethesda, MD (Presenter) Nothing to Disclose Le Lu, PhD, Bethesda, MD (Abstract Co-Author) Nothing to Disclose Xiaosong Wang, PhD, Bethesda, MD (Abstract Co-Author) Nothing to Disclose Holger R. Roth, PhD, Bethesda, MD (Abstract Co-Author) Nothing to Disclose Gedas Bertasius, Philadelphia, PA (Abstract Co-Author) Nothing to Disclose Nathan S. Lay, PhD, Bethesda, MD (Abstrac...

1 Program in Neuroscience, Uniformed Services University, Bethesda, MD, USA 2 Department of Psychiatry, Uniformed Services University, Bethesda, MD, USA 3 Center for Neuroscience and Regenerative Medicine, Uniformed Services University, Bethesda, MD, USA 4 Department of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, USA 5 Center for the Study of Traumatic Stress, ...

BACKGROUND Fine-needle aspiration (FNA) is the most dependable tool to triage thyroid nodules for medical or surgical management. However, Bethesda class III cytology, namely "follicular lesion of undetermined significance" (FLUS) or "atypia of undetermined significance" (AUS), is a major limitation of the US-FNA in assessing thyroid nodules. As the most important imaging method, ultrasound (US...

In Japan, fine-needle aspiration (FNA) cytology is the most important diagnostic modality for triaging patients with thyroid nodules. A clinician (endocrinologist, endocrine surgeon, or head and neck surgeon) generally performs FNA cytology at the outpatient clinic, and ultrasound (US)-guided FNA is widespread because US is extremely common and most clinicians are familiar with it. Although alm...

The history of “The Bethesda System” (TBS) for reporting cervical cytology goes back almost 3 decades. This terminology and the process that created it have had a profound impact on the practice of cervical cytology for laboratorians and clinicians alike. The Bethesda conferences and their ensuing output have also set the stage for standardization of terminology across multiple organs systems, ...

Background: Factor VIII administration to hemophilia A patients results in an immune response (inhibitor formation) which significantly complicates the therapy. The present study was performed to determine the prevalence of inhibitor development in hemophilia A patients receiving recombinant factor VIII therapy. Materials and Methods: This was an observational descriptive study. Clotting fac...

OBJECTIVE To assess the impact of the recommendation of the 2001 Bethesda System to report all benign-appearing endometrial cells seen in women aged > or = 40 years on the frequency with which endometrial carcinomas are potentially detected as a consequence of Pap test reports that mention endometrial cells. STUDY DESIGN We identified all women diagnosed with endometrial adenocarcinoma who al...

BACKGROUND Cytologically indeterminate thyroid nodules represent a diagnostic and therapeutic challenge. In 2007, the National Cancer Institute recommended The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) as a means of improving the accuracy of thyroid cytopathology. Our objective was to determine the effect of TBSRTC on thyroidectomy rates and malignancy risk in cytologically i...