Introduction: Down syndrome as a genetic disorder is a popular research topic in molecular studies. One way to study Down syndrome is via bioinformatics.  Methods: In this study, a gene expression profile from a microarray study was selected for more investigation. Results: The study of Down syndrome patients shows specific genes with differential expression and network centrality properties....

with the advent of ilkhan (mongols) in iran, the art of illustrating book was officially formed and, from this period onward, this art prospered. great mongolian shahnameh, the painting masterpiece of ilkhanid era, was illustrated in tabriz as the first courtly illustrated edition during the time of abu sae'd bahadorkhan; gradually afterward, other illustrated editions of shahnaneh came in...

Second level therapeutic maneuvres for controlling intracranial hypertension (ICH) proposed by the European Brain Injury Consortium and the American Association of Neurological Surgeons include barbiturates, moderate hypothermia and more recently the decompressive craniectomy (DC).In most patients, ICP can be maintained below 25 mmHg after a DC. However, the exact effect of DC on brain oxygenat...

Add 3 heavy singlet right-handed neutrinos to the minimal standard model: 1 νR for each νL. Then the operator of Eq. (3) is realized because each heavy νR is linked to νLφ 0 with a Yukawa coupling f ; and since νR is allowed to have a large Majorana mass MR, the famous seesaw realtionship mν = m 2 D/MR is obtained, where mD = f〈φ0〉. This mechanism dominates the literature and is usually implied...

Insulin resistance is a clinical condition shared by many diseases besides type 2 diabetes (T2DM) such as obesity, polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). Experimental evidence, produced over the years, suggests that metformin has many benefits in the treatment of these diseases. Metformin is a first-line drug in the treatment of overweight and obese type...

Early developmental psychologists viewed iconic representation as cognitively less complex than other forms of symbolic thought. It is therefore surprising that iconic signs are not acquired more easily than arbitrary signs by young language learners. One explanation is that children younger than 3 years have difficulty interpreting iconicity. The current study assessed hearing children's abili...

Previous research has shown implicit semantic processing of faces or pictures, but whether symbolic carriers such as words can be processed this way remains controversial. Here we examine this issue by adopting the continuous flash suppression paradigm to ensure that the processing undergone is indeed unconscious without the involvement of partial awareness. Negative or neutral words projected ...

We have developed an original planner, aSyMov, that has been specially designed to address intricate robot planning problems where geometric constraints cannot be simply “abstracted” in a way that has no influence on the symbolic plan. This paper presents the ingredients that allowed us to establish an effective link between the representations used by a symbolic task planner and the representa...

Most of the runtime failures of a software system can be revealed during test execution only, which has a very high cost. In Java programs, runtime failures are manifested as unhandled runtime exceptions. In this paper we present an approach and tool for detecting runtime exceptions in Java programs without having to execute tests on the software. We use the symbolic execution technique to impl...