In four experiments, rats were trained on different patterning discriminations before being tested with compounds composed of novel combinations of the trained stimuli. In Experiment 1, rats were trained on a negative-patterning schedule (A+ B+ AB-) intermixed with reinforced presentations of a second compound (CD+). On a subsequent test, the rats responded more to two novel compounds, AC and B...

Behcet´s disease (BD) is accepted as a systemic vasculitis. Vasculitis is observed  predominantly on the venous system. Vessel involvement is frequently seen in males. This study was planned retrospectively evaluate demographic features, clinical features, vessel involvements in BD. Furthermore, we aimed to prospectively compare consecutively chosen patients with and without thrombosis and heal...

OBJECTIVE To evaluate retinal vascular structural change in ocular Behcet's using optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). METHODS An analytic cross-sectional study of 37 eyes of 21 Behcet's uveitic patients was performed. Foveal retinal thickness (FRT), perifoveal hypoperfusion areas in superficial capillary plexus (SCP), and deep capillary plexus (DC...

PURPOSE To study the clinical characteristics of a cohort of Spanish patients diagnosed with Behcet disease and who also presented ocular inflammation. METHODS Thirty cases of Behcet disease were studied retrospectively. The authors studied age distribution, distribution by sex, clinical course, laterality, type of uveitis, secondary glaucoma, corneal involvement, hypopyon, iris-lens synechia...

Behçet disease is a systemic disease with diverse clinical symptoms which include, but not limited to, patients having oral and genital ulcers and eye involvement. We here report an 18-year-old male presenting with massive hemoptysis and cardiac arrest, having history of ulcers in the oral cavity and genitalia as well as having recent episode of uveitis. A pulmonary CT angiography revealed bila...

Oral and genital ulcers, and cutaneous vasculitic lesions are considered hallmarks of the disease, and often precede other manifestations. Mucocutaneous lesions figure prominently in the presentation and diagnosis. Therefore, their recognition may permit earlier diagnosis and treatment, with beneficial results for prognosis. This review overviews the current state of knowledge regarding the the...