Behavioral alterations can be measured as endpoints for sublethal toxicity, and serve as a tool for environmental risk assessment and analysis of toxicological impact. Numerous technical and biological factors have made sublethal effects on fish behavior difficult to quantify. In order to investigate stress- and contaminant-induced behavioral alterations, a video analysis system was designed by...

Over a number of years we have studied the phenomenology of maternal behavior from endocrine, neural, experiential, and ontogenetic perspectives. Here, we focus on the effects of early life experiences with and without the mother on subsequent maternal and non-maternal behaviors of the offspring. We have used an artificial rearing procedure, which entails removing rat pups from their mother and...

Previous investigations in male Macropodus showed that simultaneous bilateral removal of the telencephalon results in decreased sexual and nest-building behavior. The current investigation was to determine whether serial unilateral ablation of the telencephalic hemispheres, increased recovery time following simultaneous ablation, or prior spawning experience can produce savings in reproductive ...

Sex differences in neurochemical markers that correlate with behavior in aging mice NEUROBIOL AGING. We examined whether the enzymatic activities of choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) were altered similarly with age in male and female mice, and whether these changes were correlated with age-related alterations in memory and anxiety. ChAT and GAD activities we...

Maternal behavior in mammals is the result of a complex interaction between the lactating dam and her developing offspring. Slight perturbations of any of the components of the mother-infant interaction may result in alterations of the behavior of the mother and/or of the offspring. We studied the effects of exposure of female CD-1 mice to the estrogenic chemical bisphenol A (BPA) during fetal ...

This review summarizes recent brain-imaging and molecular-genetic findings on antisocial, violent, and psychopathic behavior. A ‘‘genes to brain to antisocial behavior’’ model hypothesizes that specific genes result in structural and functional brain alterations that, in turn, predispose to antisocial behavior. For instance, a common polymorphism in the monoamine oxidase A (MAOA) gene has been ...