—Driven by recent advances in batch Reinforcement Learning (RL), this paper contributes to the application of batch RL to demand response. In contrast to conventional model-based approaches, batch RL techniques do not require a system identification step, which makes them more suitable for a large-scale implementation. This paper extends fitted Q-iteration, a standard batch RL technique, to the...

BACKGROUND RNA interference (RNAi) is a specific and effective approach for inhibiting viral replication by introducing double-stranded (ds)RNA targeting the viral gene. In this study, we employed a combinatorial approach to interfere multiple gene functions of white spot syndrome virus (WSSV), the most lethal shrimp virus, using a single-batch of dsRNA, so-called "multi-WSSV dsRNA." A co-culti...

In the cow breeding process, the users also pay attention to the cow’s DHI information, especially in the keen market competition, if they want to improve the milk production, to improve the value of the milk price, to test analysis the information of DHI is of the utmost importance. However, the traditional DHI information often determines and returns the result to users by the Excel by a prof...

BACKGROUND Bioprocess development of recombinant proteins is time consuming and laborious as many factors influence the accumulation of the product in the soluble and active form. Currently, in most cases the developmental line is characterised by a screening stage which is performed under batch conditions followed by the development of the fed-batch process. Performing the screening already un...

batch sizing in different planning period is categorized as a classical problem in production planning, that so many exact & heuristic methods have been proposed to solve this problem, each of which considering various aspects of the original problem. the solution obtained from majority – e.g. mrp – is in this format that there may be some periods of idleness or each period should produ...

The aim and objective of the study was to develop herbal drug loaded niosomes as topical gel by using thin film hydration technique. The practicability of herbal drug (CODE: THDC3-2615RD) of niosomes by thin film hydration technique using Span series 20, 60, 80 and cholesterol has been successfully revealed in this study. The evolved herbal niosomes were evaluated for morphology, particle size ...

A linear (1 × 36) colorimetric sensor array has been integrated with a pre-oxidation technique for detection and identification of a variety of fuels and post-combustion residues. The pre-oxidation method permits the conversion of fuel vapor into more detectable species and therefore greatly enhances the sensitivity of the sensor array. The pre-oxidation technique used a packed tube of chromic ...

This paper presents a stochastic nonlinear model predictive control technique for discrete-time uncertain nonlinear systems with particular focus on the batch polymerization reactor application. We consider a nonlinear dynamical system subject to chance constraints (i.e. need to be satisfied probabilistically up to a pre-assigned level). This formulation leads to a finite-horizon chance-constra...

Asparaginases are the cornerstone therapy of many successful combination regimens for the treatment of acute lymphoblastic leukemia (ALL), the most common malignancy in children and adolescents. The aim of this work was to produce recombinant Erwinia carotovora L-asparaginase II in Escherichia coli fed-batch cultures. Using a robust fed-batch technique with pre-determined exponential feeding ra...