This work explores the use of both spray drying and d-glucosamine HCl (GLU) as a hydrophilic carrier to improve the dissolution rate of piroxicam (PXM) whilst investigating the electrostatic charges associated with the spray drying process. Spray dried PXM:GLU solid dispersions were prepared and characterised (XRPD, DSC, SEM). Dissolution and triboelectric charging were also conducted. The resu...

Spray atomization is a common process found in different industries, where sprays under high injection pressure are widely recorded in the literature. Nonetheless, research on spray breakup mechanism under low pressure in pharmaceutical industry is still relatively rare. Numerical model in the Lagrangian approach was modified for simulating the spray formation from a nasal spray device in the c...

This study investigates a new concept of producing precipitated calcium carbonate (PCC) from steelmaking slag and carbon dioxide via a spray carbonation process. The presented laboratory-scale spray carbonation test reactor uses a spray nozzle to disperse fine droplets of a Ca-rich solution into a spray tower, where calcium carbonate precipitates as a result of the reaction between calcium and ...

In a simulation model, the relative advantage of negative versus positive allometry of defense, that is, early versus delayed defensive investment, depends on the forms of the relationships between body size and growth, body size and mortality deterrence, and defense size and mortality deterrence. Positive allometry is favored by strongly sigmoidal growth, a strongly convex body-size/deterrence...

Objective: The aim of this work was to perform preliminary screening of the phytoconstituents present in the leaf, flower, and bark of a valuable medicinal plant, Crataeva magna (Lour.) DC. Methods: Phytochemical analysis of the leaf, flower, and bark extracts was done using various solvent by standard methods as described by Harborne (1973). Results: Six different extracts each for leaf, flowe...

Nutritional strategies to benefit skin health are of growing importance. Current approaches mainly involve nutritional supplements containing antioxidants which were initially designed to protect human skin against ultraviolet radiation-induced damage. Within recent years, however, a growing number of studies suggests that the beneficial effects of these products clearly extend beyond photoprot...

Kurchi bark and kurchi seeds have been reputed drugs in the Indian system of medicine from almost prehistoric days, being mentioned by Charak in nearly 1000 B.C. for the treatment of subacute and chronic dysenteries. Though the alkaloids were isolated as early as 1853 by Haines, and also by R. C. Dutta in the Chemical Department of the Medical College of Bengal in 1880, and whilst recently some...

Two models were developed to evaluate total volume under and over-bark of Blackwood (Acacia melanoxylon R. Br.) stand trees. By variance analysis regarding volume with and without bark it was confirmed that trees age is responsible for 48 to 50% of its volumetric behaviour. Considered the averages of those variables and regarding the three homogeneous groups of the studied sites, a single model...

Bark storage proteins (BSPs) accumulate in the inner bark parenchyma of many woody plants during autumn and winter. We investigated the effect of a short-day (SD) photoperiod on the accumulation of the 32-kilodalton bark storage protein of poplar (Populus deltoides Bart. ex Marsh.) under controlled environmental and natural growing conditions. Sodium dodecyl sulfate-polyacrylamide gel electroph...