Bacitracin may be used for presumptive differentiation of group A from other beta-hemolytic streptococci. Whatever criteria are used for the test, a small number of erroneous results will be obtained. With the 1,161 strains studied in this laboratory, using a zone of 10 mm or greater as indicative of group A was better than using Maxted's original criterion of any zone of inhibition for group A...

The technique used previously to observe complex formation between bacitracin, Mg++, and Ca5-isoprenyl pyrophosphate has been employed to measure association constants. The constant for the bacitracin A, Mg++, C55-isoprenyl pyrophosphate complex was lo6 M-I. The binding constants for other bacitracin peptides were lower and correlated with their antibiotic activities. &farnesyl pyrophosphate al...

Whole cells of Bacillus sp., bacitracin-producing bacteria, were immobilized in polyacrylamide gel prepared by using 5% total acrylamide (95% acrylamide monomer and 5% N, N'-methylenebis acrylamide). Bacitracin production by the immobilized whole cells was examined by using various fermentation media. In starch-bouillon medium, the initial activity of immobilized whole cells for bacitracin prod...

Xanthone compounds in the ethanol extract of mangosteen peel have antibacterial activity against both pathogenic and beneficial bacteria. The purpose this study was to examine effect various formulations maltodextrin from palm starch on Salmonella thypimurium Lactobacillus acidophilus. This research conducted by culturing bacterial cultures S. L. acidophilus nutrient agar (NA) media petri dishe...

Farrar, W. Edmund, Jr. (Walter Reed Army Institute of Research, Washington, D.C.), Thomas H. Kent, and Van B. Elliott. Lethal gram-negative bacterial superinfection in guinea pigs given bacitracin. J. Bacteriol. 92:496-501. 1966.-Oral administration of a single dose of bacitracin (either 2,000 or 10,000 units) was lethal to more than 80% of guinea pigs. Within the first 12 hr, there was a 2,000...

Vancoresmycin is a novel tetramic acid antibiotic, probably interfering with functions of the cytoplasmic membrane. To investigate its mode of action, mutants of Streptococcus pneumoniae exhibiting reduced susceptibility to vancoresmycin were isolated at a low frequency. Four of them were further examined and showed similar pleiotropic phenotypes, including reduced growth rate, early autolysis,...