objective: biebersteinia (geraniaceae) has a history of use in traditional medicine in some countries including iran. in the present study, cytotoxic and apoptogenic properties of hydro-ethanol extract of b. multifidi was investigated on human prostate cancer cell lines (pc3 and du 145) and human embryonic kidney 293 (hek293) cells. materials and methods: cells were cultured in rpmi-1640 medium...

Boron (B) is a non-metal micronutrient which is essential for plants growth and development. Formation of boron complex with cell wall matrix and phenolic compounds is a definite influence of boron in physiological process. It has been suggested that B-toxicity and deficiency may induce excess production of reactive oxygen species thereby promote defense responses by antioxidant enzymes or non-...

CD19 is expressed on B- lineage cells and follicular dendritic cells and plays a key role in B cell malignancies and autoimmune diseases. Thus, it has been considered as potential target for several monoclonal antibodies (mAbs). For decades, chemotherapy has been known as one of the major antitumor therapies eradicating high proliferative tumor cells. But, anti- CD19 mAbs developed for treating...

We have studied functional alteration of immunocytes in mice following inoculation of Toxocara canis second stage larvae. Results indicated depression of lymphocyte blastogenesis in response to concanavalin-A, phytohemagglutinin and allogeneic non B-cells; however, B-cell polyclonal activation was not affected as indicated by the production of total IgG. In contrast, frequency of antibody ...