Authors Yasmin Nabil El-Sakhawy, Shaimaa Abdelmalik Pessar, Noha Hussein Boshnak Ain Shams University Egypt Corresponding Author Yasmin Nabil El-Sakhawy Email: [email protected], Mobile: 1005276531 Abstract Background: CD71 or transferrin receptor is an integral membrane protein that mediates cellular iron uptake. It has been identified as a proliferation marker being expressed on many so...

In contrast to acute lymphoblastic leukemia in children, adult cases of this disease are associated with a very poor prognosis. In order to ascertain whether the frequencies and patterns of submicroscopic changes, identifiable with single nucleotide polymorphism array analysis, differ between childhood and adult acute lymphoblastic leukemia, we performed single nucleotide polymorphism array ana...

BACKGROUND Precursor B-cell acute lymphoblastic leukemia accounts for 2% of all lymphoid neoplasms in the United States and occurs most frequently in childhood, but can also occur in adults with a median age of 39 years. It is more commonly seen in males and in Caucasians. CASE REPORT We present a case of a 51-year-old Caucasian female with the development of precursor B-cell acute lymphoblas...

INTRODUCTION Acute leukemias very rarely present with jaundice. Herein we report a case of precursor B-cell acute lymphoblastic leukemia that presented with jaundice in an adult. CASE PRESENTATION A 44-year-old Hispanic man presented with right upper quadrant abdominal pain and jaundice. His initial blood work revealed pancytopenia and hyperbilirubinemia. Direct bilirubin was more than 50% of...

abstract background: high temperatures have destructive effects on cancer cells by damaging proteins and structures within cells. gold nanoparticles (aunps) can act as drug delivery vehicles, especially for cancer therapy. due to the selective intake of asparagine molecules into malignant cells, aunps were coated with asparagine; and ccrf-cem human t-cell leukemia cells were treated with the ne...

abstract background cancer diagnosis may cause deep emotional and affective problems in patients and their families.nowadays, however, despite its rising prevalence,cancer is no longer synonymous with death. given the significance of emotional well-being in cancer patients, we decided to assess the frequency of psychological problems in seven to seventeen yearolds with acute lymphoblastic leuke...

the appendix is an unusual site for extramedulary relapse in acute leukemia. the present case report describes two cases of late course acute lymphoblastic leukemia presented with leukemic infiltration of the appendix and complete remission of bone marrow. the signs and symptoms of the cases suggest that leukemic involvement of the appendix should be considered in the differential diagnosis of ...

NUDT15 genetic variants and 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia: an updated review

The significance of immunophenotyping is growing day by day. Itprovides basic information in regard to classification and prognosisof acute leukemia which helps the management of patients. Thisstudy was conducted to Identify CD markers in leukemic patientsadmitted to Tabriz, in northwestern Iran. Immunophenotyping of 60patients with acute leukemia was determined. Patients with acutemyelogenous ...