BACKGROUND Cholesteryl ester transfer protein (CETP) plays a main role in high-density lipoprotein metabolism. CETP gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (HDL-C) concentrations. The aim of this study was to determine the association of CETP -629C/A and I405V polymorphisms with coronary artery disease (C...

BACKGROUND Inflammatory bowel disease (IBD) is a chronic, relapsing, inflammatory disorder of the gastrointestinal tract that includes two entities, Crohn's disease (CD) and ulcerative colitis (UC). As with other complex diseases, both genetic susceptibility and environmental factors play role in the pathogenesis of these diseases. The tumor necrosis factor α (TNF-α) gene is located in the IBD3...

Background:Many case-control investigations have showed the correlation of TP53 gene polymorphisms with the risk of breast cancer. However, the findings are not consistent. It has been suggested that the investigation of P53 genotype combinations and haplotypes may be more helpful than the detection of single polymorphisms. In the present study, we investigate...

Thematisationis one of the troublesome areas both for translation purposes from or into English and also for learning EFL. The main reason for the problem lies in the fact that usually different languages structure thematisation in different ways. Therefore, the present research is an attempt to investigate contrastively: experiential (topical), interpersonal and textual themes in a sample of A...

conclusions the findings point to a relationship between neighborhood characteristics and obesity only in the azeri turks. however, educational level was more important than neighborhood quality in predicting the risk of obesity results three common neighborhood environments were identified: 1) modern-affluent, 2) central-high access and 3) marginal. these three factors explained 73.2% of the t...

Background: TP53 and the oncogene WRAP53 are adjoining genes, producing p53-WRAP53α sense-antisense RNA couples. WRAP53α is indispensable for p53 mRNA regulation and p53 induction following DNA damage. Up-regulated WRAP53β can induce neoplastic transformation and cancer cell survival. All these, along with the associations of WRAP53 single nu...

The present study was conducted to investigate the factors influencing ethnic solidarity among young people (18-30 years) in the Azeri regions of Khalkhal. Theoretical framework was presented using the theories Emile Durkheim, Ted Robert Gurr, George Homans, Anthony Giddens and others. The research method was survey, face validity was used and reliability was obtained by Cronbach's alpha coeffi...

Background: In addition to cellular and molecular mechanisms involved in the pathogenesis of asthma, mounting evidences demonstrate that single nucleotide polymorphisms (SNPs) in asthma relevant genes have a role in conferring susceptibility to the disease. CHI3L1 is secreted from macrophages, neutrophils, and airway epithelial cells through an IL-13 related mechanism and contributes to tissue ...