Celiac disease (CD) and type 1 diabetes (T1D) are autoimmune conditions in which dietary gluten has been proven or suggested to play a pathogenic role. In CD; gluten is established as the instigator of autoimmunity; the autoimmune process is halted by removing gluten from the diet; which allows for resolution of celiac autoimmune enteropathy and subsequent normalization of serological markers o...

Celiac disease (CD) is a common autoimmune enteropathy that occurs, in affected individuals, with exposure to gluten in the diet and improves with removal of dietary gluten. Although CD is readily considered in patients with classical presentations of the disease, atypical manifestations may be the only presenting symptoms. We present a case of CD in a 16-year-old female presenting as fever of ...

OBJECTIVE Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is caused by FOXP3 mutations. We aimed to determine the prevalence, genetics, and clinical phenotype of FOXP3 mutations in a large cohort with permanent neonatal diabetes (PNDM). RESEARCH DESIGN AND METHODS The 11 coding exons and the polyadenylation region of FOXP3 were sequenced in 26 male subjects wit...

Autoimmune enteropathy (AIE) is rare but damaging. The lack of consistent objective findings makes diagnosis a challenge. A 45-year-old male developed noninfectious diarrhea with significant weight loss and electrolyte abnormalities. Computed tomography delineated enteritis. Colonoscopy and esophagogastroduodenoscopy showed villous atrophy, chronic inflammation, and ulceration of the terminal i...

Background Celiac disease (CD) is an autoimmune mediated gluten sensitive enteropathy and a chronic inflammatory condition caused by immune pathology in the small intestines in genetically susceptible individuals. This study aimed to determine the efficacy of gluten free diet on cardiac functions using conventional and Doppler tissue echocardiography (DTE) in children with CD compared to contr...

245 Dear Editor, We describe two clinical cases of patients who first presented to ophthalmologists with bilateral serous macular elevation and generalized edema. They were later diagnosed with lupus protein‐losing enteropathy complicated with life‐threatening conditions and were treated with immunosuppressants. As ophthalmic symptoms could be the initial presentation of this disease, our repor...

La enteropatía autoinmune (EAI) es una causa infrecuente de diarrea grave asociada a un síndrome disinmune, caracterizado por la presencia de autoanticuerpos y enfermedades autoinmunes. Se revisan, de forma retrospectiva, los pacientes diagnosticados de EAI en nuestro centro desde 1975 hasta 2015. En este periodo se diagnosticaron 8 pacientes. El 75% eran varones. La edad de presentación fue: m...