نتایج جستجو برای: auto inhibition
تعداد نتایج: 354924 فیلتر نتایج به سال:
Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release
We prove that MINERVA 2, a widely-used model of biological long-term memory, is mathematically equivalent to an auto-associative memory implemented as a fourth order tensor. We further propose an alternative implementation of MINERVA 2 as a holographic lateral inhibition network. Our work clarifies the relationship between MINERVA 2 and other memory models, and shows that MINERVA 2 and derivati...
PICK1 is a neuronal scaffolding protein containing a PDZ domain and an auto-inhibited BAR domain. BAR domains are membrane-sculpting protein modules generating membrane curvature and promoting membrane fission. Previous data suggest that BAR domains are organized in lattice-like arrangements when stabilizing membranes but little is known about structural organization of BAR domains in solution....
Parkin and PINK1 function in a common pathway to clear damaged mitochondria. Parkin exists in an auto-inhibited conformation stabilized by multiple interdomain interactions. The binding of PINK1-generated phospho-ubiquitin and the phosphorylation of the ubiquitin-like (Ubl) domain of Parkin at Ser65 release its auto-inhibition, but how and when these events take place in cells remain to be defi...
OpenTuner can help users achieve better or more portable performance in their speci c domain through program autotuning. A key challenge for users seeking good autotuning performance in OpenTuner is selecting a search approach appropriate for problem. However, not only are current in-situ learning search approaches not robust enough to handle all search spaces, but there are also too many possi...
The process of empirical autotuning results in the generation of many code variants which are tested, found to be suboptimal, and discarded. By retaining annotated performance profiles of each variant tested over the course of many autotuning runs of the same code across different hardware environments and different input datasets, we can apply machine learning algorithms to generate classifier...
The traditional definition of climacteric and non-climacteric fruits has been put into question. A significant example of this paradox is the climacteric fig fruit. Surprisingly, ripening-related ethylene production increases following pre- or postharvest 1-methylcyclopropene (1-MCP) application in an unexpected auto-inhibitory manner. In this study, ethylene production and the expression of po...
in the present study the distribution of rubella hemagglutination inhibition (hi) antibody titer in the sera of 1486 women of 18 to 25 years old residing in tehran were examined. sera were pretreated with acid washed kaolin and pigeon red blood cell. titers below 1:10 and in some studies below 1:20 are considered nonimmune to rubella. our results show that 10, 29% of studied population had hi a...
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