Multilayer nanowires tailored with alternating AuFe porous layers and Au nonporous segments were fabricated by galvanic square-wave pulsed electrodeposition from a AuFe cyanide-free electrolyte. Control of porosity and composition was achieved via modulation in pulsed time and applied current density. Nanowires with decreased porosity were observed upon increasing time of the AuFe alloy layer o...

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A nanopore immunosensor is demonstrated for peanut protein Ara h1, a common food allergen. This biosensor is constructed by immobilizing the antibody to peanut protein Ara h1 within Au-coated pores of commercial nanoporous polycarbonate membranes. Peanut protein Ara h1 is detected as the change in the pore conductivity as the pores are partially obscured by antigen binding. Control experimentsw...

An extremely sensitive fluorescence sensor has been developed for selectively detection of mercury ions based on metallophilic Hg(2+)-Au(+) interactions, which results in an effective release of pre-adsorbed rhodamine 6G (R6G) molecules from the nanoporous gold substrate, associated with a significant decrease of fluorescence intensity. The optical sensor has a detection sensitivity down to 0.6...

We report a new method to produce ordered arrays of metal nanostructures on substrates. The method employs a through-hole nanoporous alumina membrane as a mask that is attached onto the substrate, silicon in this study. The material of deposition, Au in this study, was provided by pulsed laser ablation of a target gold. At an early stage of the deposition, a significant portion of Au penetrated...

Nanoparticles (NPs) have been widely explored for delivering doxorubicin (DOX), an anticancer drug, to minimize cardiotoxicity. However, their efficiency is marred by a necessity chemically modify DOX, NPs, or both and low deposition of the administered NPs on tumors. Therefore, alternative strategies should be developed improve therapeutic efficacy decrease toxicity. Here we report possibility...

Nanostructured materials with feature sizes in tens of nanometers have enhanced the performance of several technologies, including fuel cells, biosensors, biomedical device coatings, and drug delivery tools. Nanoporous gold (np-Au), produced by a nano-scale self-assembly process, is a relatively new material that exhibits large effective surface area, high electrical conductivity, and catalytic...