PURPOSE Activation of intracellular signaling cascades has been implicated in the growth control of benign meningiomas, but their role for meningioma progression and outcome is unknown. Here we determined the expression and function of proteins involved in mitogen-activated protein kinase (MAPK) and phosphinositol-3 kinase (PI3K)/Akt signaling in benign, atypical, and malignant meningiomas and ...

This article reports the first case of recurrent atypical meningioma in the third ventricle of a 12-year-old boy. As tumor invasion into cerebral tissues signifies a higher recurrence rate, complete excision of the tumor under the microscope without injury to normal cerebral tissues is essential. Follow-up examinations must be conducted for a sufficient length of time to detect early recurrence...

Three cases of intracranial dural chondrosarcoma are reported. The radiologic appearance of this slow-growing, extraaxial malignant tumor is different from the more familiar skull-base chondrosarcoma and may mimic an atypical meningioma. Dural chondrosarcoma tends to be less calcified or even to lack matrix calcification; it is associated with bone erosion but not with bone destruction or hyper...

thickened arachnoid. Cord was anteriorly adherent at D4 level. There was kinking and lateral rotation of the cord. Cord herniation through the small dural defect was identiÞ ed and reduction was done by microsurgery and the defect was closed with teß on graft. Patient had good recovery and was able to ambulate with support. Postoperative MRI revealed good reduction of the herniation and restora...

BACKGROUND a 63-year-old woman presented with an 18-year history of tremor, rigidity and akinesia. There was no response to treatment with either levodopa or pergolide. Later a focal neurological deficit developed, which led to a diagnosis of fronto-parietal meningioma. OUTCOME surgical excision of the meningioma abolished the parkinsonism. CONCLUSION cerebral tumour is an uncommon cause of...

A 15-year-old male presented with progressive weakness of both lower limbs with urinary incontinence. Magnetic resonance imaging revealed a spinal intramedullary mass at D7-D8 level. The child was operated with a preliminary diagnosis of an intramedullary tumor. Atypical ependymoma and astrocytoma were considered in the differential diagnosis. Perand post-operative histopathological examination...

A 15-year-old male presented with progressive weakness of both lower limbs with urinary incontinence. Magnetic resonance imaging revealed a spinal intramedullary mass at D7-D8 level. The child was operated with a preliminary diagnosis of an intramedullary tumor. Atypical ependymoma and astrocytoma were considered in the differential diagnosis. Per- and post-operative histopathological examinati...