Despite prophylaxis and attempts to select a therapy, the frequency of preeclampsia does not decrease it still takes leading position in structure maternal mortality morbidity worldwide. In this review, we present new theory etiology pathogenesis that is based on interaction Na/K-ATPase its endogenous ligands including marinobufagenin. The signaling pathway marinobufagenin involves an inhibitio...

We review here briefly the essentials of vertebrate cardiac pacemaking system consisting populations ion channels that drive heartbeat. In addition to sarcolemmal system, there is a second channel-based oscillator centrally reciprocating Ca2+ flow between sarcoplasmic reticulum and cytosol regulated by release through ryanodine receptors active return Sarcoplasmic/Endoplasmic Reticulum Calcium ...

background: calcium overload and free radical mediated damage in the mitochondria is the most important pathological changes associated with myocardial ischemic-reperfusion injury. the verapamil post-treatment has been previously reported to prevent reperfusion-induced myocardial injury but functional recovery may be delayed due to the drug's inherent direct myocardial depression effect. in the...

Background: Calcium overload and free radical mediated damage in the mitochondria is the most important pathological changes associated with myocardial ischemic-reperfusion injury. The verapamil post-treatment has been previously reported to prevent reperfusion-induced myocardial injury but functional recovery may be delayed due to the drug's inherent direct myocardial depression effect. In the...

(1) Background: The unusual accumulation of Na,K-ATPase complexes in the brush border membrane choroid plexus epithelial cells have intrigued researchers for decades. However, full range expressed subunits and their relation to microvillus cytoskeleton remains unknown. (2) Methods: RT-PCR analysis, co-immunoprecipitation, native PAGE, mass spectrometry, differential centrifugation were combined...

Introduction Phosphorus (P) deficiency hinders cotton ( Gossypium hirustum L.) growth and development, seriously affecting lint yield fiber quality. However, it is still unclear how P fertilizer affects length. Methods Therefore, a two-year (2019-2020) pool-culture experiment was conducted using the split-plot design, with two cultivars (CCRI-79; low-P tolerant SCRC-28; sensitive) as main plot....