Atrial fibrillation (AF) is the most frequent cardiac arrhythmia and is a major cause of morbidity and mortality. Previous studies have established genetic defects as a risk factor for AF in a minority of patients. However, AF is of substantial genetic heterogeneity and the molecular determinants for AF in a majority of cases remain unclear. In th...

Separation of Polycyclic Aromatic Hydrocarbons was performed by RP-HPLC using mixed micellar mobile phase. Effect of temperature, types and amounts of coorganic solvent in mobile phase on efficiency, asymmetry factor and selectivity factor showed that the appropriate condition for separation of these compounds was 3% isopropanol (V/V) as co-organic solvent in mobile phase at 40°C. Analysis of...

This paper aims to examine the nature of width, depth and configuration distribution along Kuya River and their temporal directionality of changes. It also pays attention to prepare some simplified indices regarding basin asymmetry, channel asymmetry and river bank stability and to explain the nature of basin and channel asymmetry and river bank stability using those constructed indices. Irregu...

BACKGROUND Patients who were hospitalized for community-based pneumonia frequently had pre-existing atrial fibrillation (AF) and had subsequent cardiovascular complications. Whether patients who had AF would be susceptible to the development of hospital-acquired pneumonia (HAP) is a serious concern but this has not been investigated. In our clinics, we have made empirical observation of such su...

AIM Accumulation level of fluorescent advanced glycation end products (AGEs) in the skin can be measured non-invasively as skin autofluorescence (skin AF) by autofluorescence reader. The aim of this study was to assess possible associations between skin AF and diabetic complications, especially early-stage atherosclerosis, in Japanese type 1 diabetic patients. METHODS Skin AF was measured by ...

OBJECTIVE Better definition of normal amplitude asymmetry values on the classical EEG frequency bands. RESULTS EEG amplitude asymmetry index (AAI) is physiologically low in normal adults, differences usually lesser than 7%. CONCLUSION Persistent or intermittent amplitude asymmetry regional differences higher than 7% may be suggestive of pathology after adequate correlation with clinical dat...

BACKGROUND Atrial fibrillation (AF) is a common arrhythmia and an important risk factor for ischaemic stroke (IS). AIM To assess the frequency of AF, including paroxysmal (pxAF), persistent (psAF) and permanent AF (pmAF), in patients hospitalised due to IS as well as to establish the natural course of AF and IS prognosis. METHODS A prospective, non-interventional study of consecutive acute ...

As a progressive atrial myopathy, the etiopathogenesis of AF is multifactorial. For example, valvular heart disease are found in 30% of AF patients and in mitral stenosis and/or regurgitation chronic atrial stretch is a well known pathophysiological factor in the occurrence of AF [1,3,4]. Indeed, mitral valve prolapse with or without regurgitation, calcification of the mitral annulus, tricuspid...

This study aimed to evaluate the relationship between serum transforming growth factor-β1 (TGF-β1) concentration and atrial fibrosis and to determine whether plasma TGF-β1 concentration is an independent predictor of atrial fibrillation (AF) recurrence after catheter ablation.We included 98 consecutive patients who underwent catheter ablation, including 38 with paroxysmal AF (AF group) and 60 w...

Abnormal survival of retinal pigment epithelium (RPE) cells contributes to the pathogenesis of proliferative vitreoretinopathy (PVR), a sight-threatening disease. In this study, we explored the effect of the anti-rheumatic agent auranofin (AF) on RPE cell survival and studied the underlying signaling mechanisms in vitro. Our results showed that AF inhibited ARPE-19 cell survival in a dose and t...