asthma is now recognized as a common cause of disability of great economic cost and preventable deaths. in this study we aimed to test our hypothesis based on the relationship between body mass index and bronchial asthma .among the patients with acute asthma admitted to the emergency ward and pulmonology clinic, we sought to determine the prevalence of obesity, as well as the effect of body mas...

BACKGROUND The sputum inflammatory cell profile is an important indicator for classifying asthma phenotypes. OBJECTIVE To investigate if sputum inflammatory cell profile remains stable and there are different characteristics between groups that show different profile over time in stable asthmatic patients. METHODS A total of 149 asthmatic patients, who were clinically stable at the time of ...

an asthmatic attack. Eighteen patients were studied during 20 separate asthmatic attacks. The patients behaved in one of three ways with regard to total lung capacity (TLC): group I had an elevated TLC during the acute asthmatic attack which returned to normal, group II had a normal TLC throughout the attack, and group III had an elevated TLC that did not return to normal on recovery from the a...

During asthma development, differentiation of epithelial cells and fibroblasts towards the contractile phenotype is associated with bronchial wall remodeling and airway constriction. Pathological fibroblast-to-myofibroblast transition (FMT) can be triggered by local inflammation of bronchial walls. Recently, we have demonstrated that human bronchial fibroblasts (HBFs) derived from asthmatic pat...

BACKGROUND The Mexico City Metropolitan Area is densely populated, and toxic air pollutants are generated and concentrated at a higher rate because of its geographic characteristics. It is well known that exposure to particulate matter, especially to fine and ultra-fine particles, enhances the risk of cardio-respiratory diseases, especially in populations susceptible to oxidative stress. The ai...

BACKGROUND The purpose of this study was to examine the relationship between the type of inhaled medication, length of use, dosing, the inhaler use technique and the severity and duration of disease on the dental caries of asthmatic patients. OBJECTIVES In the present study, the frequency of dental caries in the asthmatic patients and control group was examined. In addition the possible assoc...

OBJECTIVES Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated the burden and medical treatment of asthma during pregnancy requiring healthcare utilisation in South Korea. DESIGN Cohort study. SETTING Nationwide insurance claims database. PARTICIPANTS A total of 1,306,281 pregnant women who delivered in South Korea in 2009-201...

Background: Asthma control is the goal of asthma management. A nationwide study on this aspect was launched by Italian Society Paediatric Allergy and Immunology (ControL’Asma study). Objective: To define variables associated with different grades in a population asthmatic children adolescents. Methods: This cross-sectional real-world included 480 adolescents (333 males, median age 11.2 years) c...