toll-like receptor (tlr) 7 and 8 mediate anti-virus immunity and are of particular relevance to asthma. however, very little information about genetic association on tlr7/8 and asthma are available. this study aimed to evaluate the effects of polymorphisms in tlr7 and 8 on asthma risk and asthma-related phenotypes in a chinese han population. we enrolled 462 unrelated adult asthmatic patients a...

BACKGROUND A global definition of asthma control does not currently exist. The purpose of this study was to validate two new guideline-based composite measures of asthma control, defined as totally controlled (TC) asthma and well controlled (WC) asthma. METHODS We used data from 3416 patients randomised and treated in the multi-centre Gaining Optimal Asthma controL (GOAL) study. The criteria ...

gastro-esophageal reflux disease (gerd) regularly occurs when stomach acid moves up from the stomach into the esophagus. gerd might be associated with chronic asthma symptoms such as coughing and breathlessness. according to several studies on children and adults, gerd is proven to have a close relationship with asthma.  medication treatment via proton-pump inhibitors (ppis), such as omeprazole,...

background: asthma is a multifactorial disease and its severity varies with the inflammatory grade. there are conflicting reports about the roles of trace elements in asthma. this study examined the effects of zinc (zn), copper (cu), and selenium (se) concentrations in sera of patients with allergic asthma attending ghaem hospital, mashhad, iran. methods: forty-nine patients, aged 10 to 50 year...

Asthma is the most commonly encountered chronic disease in children. Periodic assessment of asthma severity and control is an integral part of asthma management, but patients with uncontrolled asthma don't always schedule routine asthma care visits. The aim of this project was to improve asthma control and severity screening in a primary care setting by using a validated tool for all visits for...

Both the National Asthma Education and Prevention Program Expert Panel Report 3 and the 2015 Global Initiative for Asthma guidelines identify achieving and maintaining asthma control as goals of therapy, and they emphasize periodic assessment of asthma control once treatment is established. Accurate assessment of asthma control is difficult due to the complexity of asthma control and due to the...

objectives the current study aimed to investigate h. pylori seropositivity in children with and without asthma. patients and methods this cross-sectional study was performed with 208 children aged 5- to 12-years-old (104 asthmatic subjects in the case group and 104 healthy individuals in the control group) who had been referred to the pediatric clinic of amir kabir hospital in arak, iran. h. py...