نتایج جستجو برای: associated protein bap

تعداد نتایج: 2524810  

Journal: :Pathobiology : journal of immunopathology, molecular and cellular biology 2010
Weihua Wu Zhenjie Sun Jiangpo Yu Qinghui Meng Mingli Wang Jiajing Miao Lifang Sun

OBJECTIVE Apathetic hyperthyroidism can be misdiagnosed or diagnosed late, and older patients are often susceptible to adverse effects of treatment for thyrotoxicosis. The aim of this study was to identify factors associated with apathetic hyperthyroidism. METHODS We retrospectively examined serum calcium, phosphorus and bone-specific alkaline phosphatase (BAP) levels and thyroid-associated v...

Journal: :The Journal of general virology 2012
G De Lorenzo C Eichwald E M Schraner V Nicolin R Bortul M Mano O R Burrone F Arnoldi

Although inserting exogenous viral genome segments into rotavirus particles remains a hard challenge, this study describes the in vivo incorporation of a recombinant viral capsid protein (VP6) into newly assembled rotavirus particles. In vivo biotinylation technology was exploited to biotinylate a recombinant VP6 protein fused to a 15 aa biotin-acceptor peptide (BAP) by the bacterial biotin lig...

2015
Zs. Csanádi A. Szabó Nagy J. Szabó J. Erdős

The main objective of this study was to assess the annual concentration and seasonal variation of benzo(a)pyrene (BaP) associated with PM10 in an urban site of Győr and in a rural site of Sarród in the sampling period of 2008–2012. A total of 280 PM10 aerosol samples were collected in each sampling site and analyzed for BaP by gas chromatography method. The BaP concentrations ranged from undete...

Journal: :international journal of reproductive biomedicine 0
elaheh mesdaghi-nia mitra behrashi arezoo saeidi masoomeh abedzadeh kalahroodi

background: measuring of maternal serum pregnancy-associated plasma protein-a (papp-a) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta.objective: the aim was to determination of association between placental thickness in second trimester with low level of papp-a in first trimester.materials and methods: in this cohort study, serum papp-a of...

2016
Wenping Zhang Fengjie Tian Jinping Zheng Senlin Li Mei Qiang Weijing He

BACKGROUND Recently, an increasing number of human and animal studies have reported that exposure to benzo(a)pyrene (BaP) induces neurological abnormalities and is also associated with adverse effects, such as tumor formation, immunosuppression, teratogenicity, and hormonal disorders. However, the exact mechanisms underlying BaP-induced impairment of neurological function remain unclear. The ai...

Journal: :Environmental Science and Pollution Research 2021

Fish have defense systems that are capable of repairing damages caused by xenobiotics like benzo[a]pyrene (BaP), so the aims this study were to identify BaP toxicity in melanomacrophages (MMs) cytoskeleton, evaluate melanin area MMs, and analyze genotoxicity. Rainbow trout juveniles (n = 24) split 48h 7d treatments received 2 mg/kg BaP. After experiment, blood samples collected liver was remove...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2004
Jeanine A Harrigan Chad M Vezina Barbara P McGarrigle Noreen Ersing Harold C Box Alexander E Maccubbin James R Olson

Chemical-DNA adducts provide an integrated measure of exposure, absorption, bioactivation, detoxification, and DNA repair following exposure to a genotoxic agent. Benzo[a]pyrene (BaP), a prototypical polycyclic aromatic hydrocarbon (PAH), can be bioactivated by cytochrome P-450s (CYPs) and epoxide hydrolase to genotoxic metabolites which form covalent adducts with DNA. In this study, we utilize...

Journal: :Mutation research. Genetic toxicology and environmental mutagenesis 2014
Françoise Vincent-Hubert Amélie Châtel Catherine Gourlay-Francé

We have previously shown that cadmium (Cd) and benzo[a]pyrene (BaP) induced early DNA damages in zebra mussels, and that the level of DNA strand breaks (SB) returned to a basal level after 3 days of exposure to Cd. The aim of the present study was to go further in the mechanisms of Cd and BaP detoxification. For that purpose, expression of genes encoding for metallothionein (MT), aryl hydrocarb...

Journal: :The Journal of Cell Biology 1985
D T Wong D K Biswas

Human lung cells (ChaGo) derived from a bronchogenic carcinoma synthesize and secrete in the culture medium the alpha subunit of the glycoprotein hormone, human chorionic gonadotropin (alpha-hCG). The synthesis of alpha-hCG by ChaGo cells could be further stimulated by treatment with sublethal concentrations of the polycyclic aromatic hydrocarbons (PAHs), benzo(a)pyrene (BaP), or dimethylbenzan...

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