نتایج جستجو برای: associated lipocalin protein

تعداد نتایج: 2522999  

2017
Kangmin Yang Han‐Bing Deng Andy W.C. Man Erfei Song Jialiang Zhang Cuiting Luo Bernard M.Y. Cheung Kwok‐Yung Yuen Pia Søndergaard Jensen Akhmadjon Irmukhamedov Atlanta G.I.M. Elie Paul M. Vanhoutte Aimin Xu Jo G.R. De Mey Yu Wang

AIMS Lipocalin-2 is a pro-inflammatory molecule characterized by a highly diversified pattern of expression and structure-functional relationships. In vivo, this molecule exists as multiple variants due to post-translational modifications and/or protein-protein interactions. Lipocalin-2 is modified by polyamination, which enhances the clearance of this protein from the circulation and prevents ...

Journal: :European journal of endocrinology 2011
Xiaowen Liu Ole-Petter R Hamnvik Michael Petrou Huizhi Gong John P Chamberland Costas A Christophi Stefanos N Kales David C Christiani Christos S Mantzoros

OBJECTIVE Lipocalin 2 (LCN2 or NGAL), a protein derived from neutrophils, macrophages, adipocytes, and other cells, has been proposed to be a link between obesity and insulin resistance (IR), but animal and cross-sectional human studies have revealed conflicting results. We studied the association of serum lipocalin 2 with anthropometric, metabolic, and cardiovascular risk markers in young heal...

2015
Miho Suzuki Sachiko Takahashi Takanori Kondo Hideo Dohra Yumihiko Ito Yoshikazu Kiriiwa Marina Hayashi Shiori Kamiya Masaya Kato Masayuki Fujiwara Yoichiro Fukao Megumi Kobayashi Noriko Nagata Reiko Motohashi Hany A. El-Shemy

To better understand the mechanism of plastid differentiation from chloroplast to chromoplast, we examined proteome and plastid changes over four distinct developmental stages of 'Micro-Tom' fruit. Additionally, to discover more about the relationship between fruit color and plastid differentiation, we also analyzed and compared 'Micro-Tom' results with those from two other varieties, 'Black' a...

Journal: :International journal of translational medicine 2022

Urinary tract infections (UTIs) are among the most common infective disease in adult population. UTI diagnosis is based essentially on presence of lower urinary symptoms (e.g., dysuria, urgency, and frequency) evidence bacteriuria (by dipstick testing and/or urine culture). not always easy because can be vague, or patient basal conditions interfere negatively with diagnostic process, whereas cu...

Journal: :Acta biochimica et biophysica Sinica 2015
Baoquan Song Hairui Zhang Lei Jiang Ying Chi Jianjian Tian Wenjing Du Bentong Yu Zhongchao Han

Lipocalin 2 (LCN2), a multifunctional secretory protein known as neutrophil gelatinase-associated lipocalin (NGAL), is expressed in a variety of cancers. However, little is known about the biological functions of NGAL in the development of lung adenocarcinoma. In the present study, we primarily found that NGAL expression was up-regulated in human lung adenocarcinoma tissues. Additionally, deple...

Journal: :Molecular biology and evolution 2000
M D Ganfornina G Gutiérrez M Bastiani D Sánchez

The lipocalins are a family of extracellular proteins that bind and transport small hydrophobic molecules. They are found in eubacteria and a great variety of eukaryotic cells, in which they play diverse physiological roles. We report here the detection of two new eukaryotic lipocalins and a phylogenetic analysis of 113 lipocalin family members performed with maximum-likelihood and parsimony me...

2017
Anastasia Asimakopoulou Erawan Borkham-Kamphorst Eddy Van de Leur Ralf Weiskirchen

The data presented in this brief report support the research article "Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis" [1, doi: 10.1016/j.bbadis.2017.04.006]. We tested whether the absence of Lipocalin-2 (LCN2) could dysregulate the phosphatidylinositol 3-kinase/protein kinase B (PI3K-PKB) pathway and hepatic homeostasis in Non-Alcoholic-Stea...

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