نتایج جستجو برای: aspirin hypersensitivity
تعداد نتایج: 58196 فیلتر نتایج به سال:
Since the discovery of the anaesthetic effect of cocaine in 1884, local anaesthetics (LAs) have been widely used. It has been estimated that 6 million people are injected with LAs each day around the world. In spite of their widespread use, true hypersensitivity appears to be infrequent. However the perception of allergy to LA among the general public is high. In our drug allergy clinic, referr...
Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyposis and aspirin hypersensitivity. The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation. Recently, it has been reported that the expression of discoidin, CUB and LCCL domain-containing protein 2 (DCBLD2) is up-regulated in lung cancers ...
AERD is an organ-specific disease, characterized by abnormalities in the biosynthesis of eicosanoid mediators and eicosanoid receptor expression. The biochemical hallmark of AERD is enhanced cysteinyl leukotriene (CysLT) production both at baseline [9, 10] and following aspirin challenge [11, 12] . As AERD is not a systemic disease, it is not surprising that studies of different inflammatory ce...
conclusions the characteristic features of ige-mediated food allergy are abrupt onset of clinical symptoms, which may result in a life-threatening events, and positive results of the majority of the paraclinical tests that mainly trace the specific ige to foods. moreover, non–ige-mediated food allergies present as chronic diseases and due to lack of proper diagnostic tests the similarity of the...
Background: Paracetamol (acetaminophen, N-acetyl-para-aminophenol) is a well-known antipyretic and analgesic drug. Hypersensitivity reactions to paracetamol are rare. However, we report seven cases of anaphylaxis to paracetamol and a review of the literature. Procedure: Between January 1999 and May 2012, we diagnosed seven cases of anaphylaxis to paracetamol in our Allergy Department of Hospita...
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